I've known about "Serrapeptase" for over 30 years, and have been taking it just as long. I am now 78 years old, and my bony hands, feet, back, etc. show a long familiarity with arthritis and other bone/muscle,joints, etc. ailments. I do not know why the various vendors of it now never mention its amazing and award winning history, but it has been used to treat many diseases and conditions. My bony fingers show the attempted attack of arthritis, my back is bent over with the follow-up condition to scoliosis, kyphosis. BUT, I have NO pain in my hands and fingers! For all of its torturous bending, my back is kept mobile, and simple over the counter "pain relievers - aspirin and/or ibueprophen" keep me up and going! Sadly doctors do not know, or RATHER PREFER not to know about the Japanese discovery, as they can't make "any money on it"!. But, Serrapeptase, as we call it in the US, is a GODSEND to anybody that has used it! There ARE a number of helpful articles about it on the internet. I recommend anybody interested go find and read some of them.