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Many people consider Adrafinil to be the most potent nootropic available that does not require a prescription. It has been proven to enhance a wide range of cognitive functions including memory, focus, energy, and problem solving ability. It has also been shown to positively effect mood and increase levels of motivation. It is the perfect nootropic for students looking to pick up an extra edge in the classroom or employees who experience mental or physical fatigue during the work day.
The recommended dosage of Adrafinil is 300 mg, although some people have reported needing 600 mg to experience it’s full benefits. It’s recommended to start at a 300 mg dose, and to only increase the dosage if you find this dosage to be insufficient.
Taking doses higher than 600 mg at once not only increases the possibility of experiencing adverse side effects, but may even reduce the effectiveness of the compound.
Unlike amphetamines and related stimulants, Adrafinil does not cause any anxiogenic (anxiety causing) side effects or other side effects resulting from stimulation of the peripheral nervous system.  That said, Adrafinil has been known to cause the following side effects in some individuals:
Most important to note is that Adrafinil has been shown to increase counts of liver enzymes when taken regularly, suggesting that sustained use could cause liver damage. It’s effect on liver enzyme profiles is small and has been shown to be similar to that of tylenol. This means that while infrequent use isn’t likely to cause liver damage, like with Tylenol Adrafinil should never be taken with alcohol and any drugs shown to have similar effects on liver enzymes.