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Liver Supplements


  • Best Seller

    TUDCA Supplement

    Liver Health

    From

    $ 27.95

  • Best Seller

    Berberine Supplement

    Metabolism
    Heart & Vessels
    Liver Health

    From

    $ 19.95

  • Liquid Chlorophyll Supplement

    Gut Health
    Hair Skin and Nails

    From

    $ 19.95

  • Vitamin D3 + K2 Liquid Drops

    Immune Health
    Bone & Joint
    Hormone Balance

    From

    $ 19.95

  • N-Acetyl Cysteine (NAC) Supplement

    Liver Health
    Antioxidants
    Brain Health

    From

    $ 29.95

  • Zinc Picolinate Supplement

    Immune Health
    Heart & Vessels

    From

    $ 19.95

  • S-Acetyl L-Glutathione Supplement

    Antioxidants
    Gut Health
    Liver Health

    From

    $ 32.95

  • Liposomal Glutathione Supplement

    Gut Health
    Antioxidants
    Liver Health

    From

    $ 29.95

  • Phosphatidylcholine Complex Supplement

    Brain Health
    Focus & Energy

    From

    $ 19.95

  • Glycine Supplement

    Sleep
    Anxiety & Stress

    From

    $ 19.95

  • DHM 1000 Supplement

    Liver Health

    From

    $ 29.95

  • Ox Bile Salt Supplement

    Immune Health
    Gut Health

    From

    $ 19.95

  • Milk Thistle Drops

    Liver Health
    Gut Health

    From

    $ 19.95

  • Astragalus Supplement

    Immune Health
    Liver Health

    From

    $ 19.95

  • Sold out

    DHM Supplement

    Liver Health

    $ 14.95

  • Cistanche Extract Supplement

    Antioxidants
    Liver Health

    From

    $ 19.95

  • Dihydromyricetin DHM (50 ct.)

    Liver Health

    $ 19.95

  • Dihydromyricetin DHM (90 ct.) Supplement

    Liver Health

    $ 24.95

  • Bee Pollen Supplement

    Antioxidants
    Heart & Vessels
    Liver Health

    $ 24.95

Overview

The liver performs over 500 metabolic functions — from filtering toxins and metabolizing drugs to synthesizing proteins and regulating blood sugar. Protecting and supporting liver function is one of the highest-leverage investments in overall health, yet it is often overlooked until a problem emerges. Double Wood's liver health collection features the most evidence-backed hepatoprotective and liver-supportive ingredients available, each in precisely dosed, single-ingredient form.

What To Look For

TUDCA (Tauroursodeoxycholic Acid) is one of the most discussed liver supplements in clinical circles — it has direct evidence for protecting hepatocytes from bile acid-induced stress and is the most effective single supplement for liver enzyme support. Milk Thistle (silymarin) has decades of research supporting its use in liver protection and regeneration. Glutathione (in S-Acetyl and Liposomal forms) addresses oxidative stress in liver tissue specifically. NAC supports glutathione synthesis in the liver, making it particularly relevant for detoxification support. DHM (Dihydromyricetin) — the ingredient that first brought Double Wood to market in 2013 — is studied for alcohol metabolism and acute liver support. Berberine supports liver health through its effects on lipid and glucose metabolism.

Frequently Asked Questions

What is TUDCA and why do people take it for liver health?
TUDCA is a water-soluble bile acid that occurs naturally in the body. It is studied for its ability to protect liver cells from damage caused by bile acid accumulation, oxidative stress, and certain toxins. In clinical settings it has been used for cholestatic liver conditions. Among supplement users, it is most commonly taken to support liver health during periods of high metabolic demand — such as when taking other compounds that are hepatically metabolized.
What is the best supplement for liver health and detoxification?
TUDCA and Milk Thistle are the two most clinically supported options for general liver protection. For detoxification specifically, NAC and Glutathione (particularly Liposomal Glutathione for absorption) are the most relevant options, as they support the liver's Phase II detoxification pathways. DHM is specifically studied for supporting the liver's metabolism of alcohol. TUDCA and NAC are frequently paired for comprehensive hepatic support.
What is DHM and how does it support the liver?
Dihydromyricetin (DHM) is a flavonoid from the Japanese raisin tree (Hovenia dulcis) with a long history of use in traditional East Asian medicine for alcohol-related complaints. Research suggests it supports the liver's ability to metabolize acetaldehyde, a toxic byproduct of alcohol metabolism. It is Double Wood's original product — the one that launched the company in 2013.
- All Double Wood supplements are single-ingredient, third-party tested for purity and potency, and manufactured in cGMP-certified U.S. facilities. Certificates of Analysis are available for every product.