What is TUDCA and why do people take it for liver health?
TUDCA is a water-soluble bile acid that occurs naturally in the body. It is studied for its ability to protect liver cells from damage caused by bile acid accumulation, oxidative stress, and certain toxins. In clinical settings it has been used for cholestatic liver conditions. Among supplement users, it is most commonly taken to support liver health during periods of high metabolic demand — such as when taking other compounds that are hepatically metabolized.
What is the best supplement for liver health and detoxification?
TUDCA and Milk Thistle are the two most clinically supported options for general liver protection. For detoxification specifically, NAC and Glutathione (particularly Liposomal Glutathione for absorption) are the most relevant options, as they support the liver's Phase II detoxification pathways. DHM is specifically studied for supporting the liver's metabolism of alcohol. TUDCA and NAC are frequently paired for comprehensive hepatic support.
What is DHM and how does it support the liver?
Dihydromyricetin (DHM) is a flavonoid from the Japanese raisin tree (Hovenia dulcis) with a long history of use in traditional East Asian medicine for alcohol-related complaints. Research suggests it supports the liver's ability to metabolize acetaldehyde, a toxic byproduct of alcohol metabolism. It is Double Wood's original product — the one that launched the company in 2013.