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Alpha GPC Supplement

$ 19.95

600mg of Alpha-GPC (L-Alpha glycerylphosphorylcholine) per serving, providing 300mg active, a phospholipid-bound choline compound designed to support attention, mental clarity, and cognitive performance,* manufactured in the USA. Every batch tested. Third-party tests by ISO/IEC 17025 accredited labs. COAs published openly.
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Description

Alpha-GPC (L-Alpha glycerylphosphorylcholine) is a phospholipid-bound form of choline that is among the most bioavailable choline compounds available in supplement form. Unlike choline bitartrate or lecithin-based sources, Alpha-GPC crosses the blood-brain barrier efficiently, delivering choline directly to neurons, providing the building block the body uses to produce acetylcholine and supporting phosphatidylcholine levels in neuronal membranes. Acetylcholine is the neurotransmitter most directly associated with attention, learning, working memory, and cognitive performance, making Alpha-GPC a strong fit for those building more intentional daytime cognitive wellness routines.*

Double Wood's Alpha-GPC delivers 600mg per serving (2 capsules), providing 300mg of active Alpha-GPC. Best taken in the morning or early afternoon; avoid late-day use as its cognitive support properties* may interfere with evening wind-down for some individuals. Note: if you are already using a choline-based product such as CDP-Choline or choline bitartrate, consult your healthcare provider before adding Alpha-GPC, combining multiple choline sources is generally not necessary for most users. Manufactured in the USA in a cGMP-certified facility. Every batch tested. Third-party tests by ISO/IEC 17025 accredited labs. COAs published openly.

Soy-Free, Gluten-Free, Non-GMO

Benefits
  • Phospholipid-bound choline, efficient brain delivery. Alpha-GPC is a phospholipid-bound choline compound that crosses the blood-brain barrier more efficiently than basic choline salts, delivering choline directly to neurons, providing the building block the body uses to produce acetylcholine, and supporting neuronal membrane structure.*
  • Supports attention, mental clarity, and daytime focus. Alpha-GPC provides choline, a nutrient the body uses to produce acetylcholine, the neurotransmitter most directly associated with attention, working memory, and cognitive performance, making it a strong fit for performance-oriented daytime cognitive routines.*
  • 600mg per serving, providing 300mg active. Each serving (2 capsules) delivers 600mg of Alpha-GPC, providing 300mg active, in a straightforward daily capsule format.*
  • Best used as a standalone primary choline source. Alpha-GPC is most effective when used as a dedicated choline source rather than combined with other choline compounds.* Adding multiple choline products generally increases complexity without proportional benefit for most users.
  • Every batch tested for purity, potency, heavy metals, and microbial safety. Third-party tests by ISO/IEC 17025 accredited labs. COAs published openly. Results available on this page by lot number.

Directions & Dosage

Take 2 capsules daily, with or without food, preferably in the morning or early afternoon. Avoid taking late in the day as Alpha-GPC's cognitive support properties* may interfere with evening wind-down routines for some individuals. If you are currently using another choline-based supplement, consult your healthcare provider before adding Alpha-GPC. Consult your provider for personalized guidance on serving size and timing.

The Science Behind Alpha-GPC (L-Alpha glycerylphosphorylcholine)

Acetylcholine Support and Cognitive Performance Alpha-GPC's primary mechanism is its efficient delivery of choline to the brain, providing the building block the body uses to produce acetylcholine. Acetylcholine is the neurotransmitter most directly involved in attention, working memory, and the encoding of new information, making choline availability a key determinant of cognitive performance under demand. A randomized, double-blind, placebo-controlled study published in the Journal of the International Society of Sports Nutrition (Ziegenfuss et al., 2008) found that Alpha-GPC supplementation supported reaction time, peak force, and cognitive performance in healthy young adults, establishing it as one of the few choline compounds with direct evidence for acute cognitive and performance support.*

Alpha-GPC vs. Other Choline Sources The primary distinction between Alpha-GPC and other choline supplements is bioavailability and mechanism. Choline bitartrate and lecithin provide choline but are less efficiently transported across the blood-brain barrier. CDP-Choline (citicoline) provides choline alongside cytidine, adding phospholipid synthesis pathway support via uridine. Alpha-GPC provides choline bound to glycerophosphate, with particularly efficient blood-brain barrier crossing and direct acetylcholine pathway support. For those focused specifically on attention, mental clarity, and performance-oriented cognition, Alpha-GPC's targeted mechanism makes it the more direct option.*

Research on Performance and Cognitive Support Beyond the Ziegenfuss study, Alpha-GPC has been examined in the context of broader cognitive and performance support. A study published in the Journal of the International Society of Sports Nutrition (Bellar et al., 2015) found that Alpha-GPC supplementation supported peak force during lower body strength assessment in resistance-trained individuals, while additional research has examined its effects on cognitive wellness across different age groups.*

View Latest Test Results

Third-party tested for quality and purity

This production lot was tested for ingredient potency, capsule weight, disintegration, heavy metals, and microbial quality.

Test Claim or Limit Result
Potency
Alpha GPC 50% (L-alpha-glycerylphosphorylcholine) 270-375 mg 294 mg
Physical Testing
Capsule Weight 481-507 mg 495 mg
Disintegration Not more than 30 minutes Passed
Heavy Metals
Arsenic <10 µg/serving 0.156 µg/serving
Cadmium <4.1 µg/serving 0.062 µg/serving
Lead <0.5 µg/serving 0.071 µg/serving
Mercury <0.3 µg/serving <0.000 µg/serving
Microbial Testing
Total Plate Count <1,000 CFU/g 20 CFU/g
Total Yeast & Mold Count <100 CFU/g <10 CFU/g
E. coli Absent Absent
Salmonella spp. Absent Absent
Staphylococcus aureus Absent Absent

Lot: 2517000Manufactured: 08/2025

Lab: Brand Nutraceuticals, Inc.

View Certificate of Analysis (PDF)

See the original Certificate of Analysis for complete testing details, methods, and laboratory documentation.
View Certificate of Analysis View Third Party Test Results
Identity, potency, and contaminants verified per batch Identity, potency, and contaminants verified per batch
Manufactured in an FDA-registered cGMP facility Manufactured in an FDA-registered cGMP facility
Manufactured in the USA from Globally Sourced Materials Manufactured in the USA from Globally Sourced Materials

Benefits

  • Powerful Bioavailable Choline Support - Alpha GPC is the most bioavailable form of Choline currently available. Choline is a water-soluble nutrient which acts as a precursor to the neurotransmitter Acetylcholine, making Double Wood's Alpha GPC Choline Capsules easily absorbed by the body and fast acting.
  • Advanced Memory Formula - Double Woods Supplements' Alpha GPC Choline Supplement memory pills supports cognitive function, including memory, learning, and focus
  • Supports Acetylcholine Levels - Our Alpha GPC is a precursor to the neurotransmitter Acetylcholine, which supports memory and brain function. Alpha GPC brain pills supports brain health, especially as one ages
  • Monthly Supply - Each container of our Alpha GPC Choline brain health supplement contains 60 capsules allowing you to experience its potential benefits for a full month if taken as directed.
Benefits

Alpha-GPC (L-Alpha glycerylphosphorylcholine)

Alpha-GPC (L-Alpha glycerylphosphorylcholine) is a naturally occurring phospholipid found in the brain and in human breast milk. As a supplement, it is derived from soy or sunflower lecithin through an enzymatic purification process. Its phospholipid structure allows it to cross the blood-brain barrier more efficiently than water-soluble choline salts such as choline bitartrate, making it one of the most bioavailable choline sources available. In the brain, Alpha-GPC is cleaved into choline and glycerophosphate, providing choline the body uses to produce acetylcholine and support phosphatidylcholine levels in neuronal membranes, while glycerophosphate contributes to cell membrane structural support.* This direct choline delivery mechanism distinguishes Alpha-GPC from more complex choline compounds and makes it the preferred choice for those focused specifically on acetylcholine support and performance-oriented cognitive wellness.* Double Wood's formula delivers 600mg per serving, providing 300mg of active Alpha-GPC.

Alpha-GPC (L-Alpha glycerylphosphorylcholine)

What Customers Are Saying

Reviews

"Reputation of product and overall delivery and ordering experience has always been a good experience."

Jacqueline P.

"Always fast shipping and great selection no matter what you’re looking for."

Aaron B.

"Double Wood is always my go-to for supplements. Great, effective, clean products and always at a reasonable price."

Jan W.

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Supplement Facts

Pairs well with

Powerful alone, stronger together. Alpha GPC Supplement delivers targeted support on its own, but combining it with complementary ingredients can help create a more holistic and balanced approach to wellness.

  • Phosphatidylserine Supplement

    Phosphatidylserine is essential for brain health and cognitive function, supporting memory and focus for an energized mind.

  • L-Theanine Supplement

    L-Theanine offers a natural way to promote relaxation and calmness, helping you unwind without feeling drowsy.

Frequently Asked Questions

What does Alpha-GPC do, and what is it used for?

Alpha-GPC is a phospholipid-bound choline compound used to support attention, mental clarity, and cognitive performance.* It crosses the blood-brain barrier efficiently and provides choline, a nutrient the body uses to produce acetylcholine, the neurotransmitter most directly associated with attention, working memory, and focus. Double Wood's formula delivers 600mg per serving (2 capsules), providing 300mg of active Alpha-GPC.

What is the difference between Alpha-GPC and CDP-Choline?

Both are bioavailable choline compounds but work through different mechanisms. Alpha-GPC provides choline bound to glycerophosphate for efficient blood-brain barrier crossing and direct acetylcholine pathway support, making it more performance and focus-oriented.* CDP-Choline provides choline alongside cytidine, adding uridine and brain phospholipid synthesis support, making it more clarity and brain health-oriented.* Most people use one as their primary choline source. Combining both is generally not necessary and adds complexity without proportional benefit for most users.

How much Alpha-GPC should I take per day and when?

Double Wood Alpha-GPC delivers 600mg per serving (2 capsules), providing 300mg of active Alpha-GPC. Take 2 capsules in the morning or early afternoon as part of a consistent daytime cognitive routine. Avoid late-day use as Alpha-GPC's cognitive support properties* may interfere with evening wind-down for some individuals. Consult your healthcare provider for personalized guidance.

Is Alpha-GPC safe to take daily, and are there side effects?

Alpha-GPC is generally well-tolerated for daily use at recommended serving sizes. Mild headache, digestive discomfort, or heightened alertness may occur in some individuals. Those combining Alpha-GPC with other choline-based supplements should be aware that excessive choline intake may cause headache, digestive upset, or a fishy body odor in sensitive individuals. Alpha-GPC is most effective as a standalone primary choline source. Those who are pregnant, nursing, or taking prescription medications should consult their healthcare provider before use.

Is Double Wood Alpha-GPC third-party tested, and where can I find the COA?

Every batch is tested for purity, potency, heavy metals, and microbial safety. Third-party tests by ISO/IEC 17025 accredited labs. COAs published openly. Searchable by lot number on this product page.

Is Double Wood Alpha GPC third-party tested?

Yes. Every batch is third-party tested by an ISO/IEC 17025-accredited laboratory for identity, Alpha GPC content, heavy metals, and microbial safety. Alpha-glycerylphosphorylcholine (Alpha GPC) is verified by HPLC against reference standards. The raw material is standardized to 50% Alpha GPC by weight (the industry norm — pure Alpha GPC is hygroscopic and unstable at higher concentrations), with mannitol and silica as standard carriers. The full COA panel also covers four heavy metals via ICP-MS (arsenic, cadmium, lead, mercury against USP <2232> limits) and six microbial screens (TPC, Yeast & Mold, Coliform, E. coli, Salmonella, Staph aureus per USP and AOAC methods). Manufactured in a cGMP-certified U.S. facility.

What does the Alpha GPC Certificate of Analysis confirm?

The COA verifies 300 mg of Alpha GPC 50% per capsule (delivering approximately 150 mg of active alpha-glycerylphosphorylcholine), or 600 mg per 2-capsule serving (delivering ~300 mg active). Content is measured by HPLC against the Alpha GPC reference standard. Heavy metals: arsenic, cadmium, lead, and mercury all verified below USP <2232> daily-intake limits via ICP-MS. Microbial counts within USP <2021>/<2022> specifications; E. coli, Salmonella, and Staphylococcus aureus confirmed Absent. The current batch COA is linked above for verification against the lot number on your bottle.

Overall rating: 4.733333 / 5 from 15 reviews.

AI Generated Review Summary

Summary topics

Review topics: ["ingredients","energy","effect","supplement","memory","enhancer"].

Review highlights

Reviews

"It really helps my memory! I’ve been taking these for a while now and they really work. I’m very pleased with them."

— Vicki (5/5)

"Don’t notice anything specific to this…so may be a bust in my opinion"

— Alfred (2/5)

Pretty Neat Effect!

"I've been noticing that I was losing concentration at my Thursday evening Poker game. In fact I had a month of losses racked up. I started taking Alpha GPC (heard about it on a Huberman Podcast) and the very next game I paid for my order! Been winning since!!"

— MICHAEL M. (5/5)

Not for me

"It’s not giving me any added energy. Focus and memory. No"

— Linda m. (5/5)

Excellent

"Products are impeccable, but prices exorbitant. I am searching for a complete modicum of natural nutritive. As a naturopathic pharmacist and Holistic health Practitioner I want to be a provider of supremely efficacious and affordable items."

— Paul M. (4/5)

great cognitive AND muscle strength aid

"I love your Alpha-GPC, it is a great cognitive enhancer, focus and attention are much improved AND muscle strength is a great improvement as well. Keep doing the good work."

— CARMEN S. (5/5)

Strong Cognitive Effects

"I mainly tried Alpha GPC for its effects on memory and after about a month of daily usage, I noticed my memory was much sharper. It a lot in active recall for my studies."

— Max (5/5)

Absolute mandatory supplement

"At any age, especially in 4th quarter of your life, you have consumed things that depletes your choline. Alpha GPC Restores it and heads off dementia."

— Michael P. (5/5)

Good product

"Good products, yet gotta work on your customers service via phone call"

— jason j. (5/5)

Quality product

"I find this form of choline superior to others. The plus is the competitive price."

— Arthur S. (5/5)

Q&A

Is the gelatin pork gelatin?
Our gelatin is bovine. We hope this helps.
1200 mg. a day is the standard recommended dosage for Alpha GPC to improve cognition in studies. Your product says it is 50% Alpha Gpc at 600 mg. Does that mean that in order to receive the 1200 mg of Alpha GPC a person would need to take 8 capsules of your product a day? Your product is not clear on this.
The standard recommended dose for Alpha GPC (Alpha-Glycerylphosphorylcholine) can vary depending on the intended use, but general guidelines suggest the following: For Cognitive Enhancement: A typical dose is 300-600 mg taken once or twice daily. For Athletic Performance: A common dose is around 600-1200 mg taken 30-60 minutes before exercise. For General Use: A dose of 300-600 mg per day is generally recommended. It&#x27;s important to start with a lower dose to assess tolerance and consult with a healthcare professional before starting any new supplement regimen.

Alpha GPC Supplement

From

$ 19.95

Primary Benefit

Brain Health

Other Benefits

Focus & Energy

Product Form

Capsule
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