NMN Supplement

The best time to take NMN (Nicotinamide Mononucleotide) is in the morning, as it aligns with the body's natural circadian rhythm and may support energy production throughout the day so you can feel your best. However, some prefer splitting the dose between morning and early afternoon due to NMN's half-life.

A typical daily dosage of NMN ranges from 250 to 500 mg, although some studies suggest doses up to 1,000 mg may be safe. It's best to start with a lower dose and gradually increase it, depending on your individual needs and tolerance.

Harvard aging researcher Dr. David Sinclair has publicly described taking 1,000 mg (1 gram) of NMN in the morning along with approximately 1,000 mg of resveratrol. He has also described mixing his resveratrol with a small amount of yogurt or olive oil because resveratrol is poorly soluble in water.

This is Sinclair’s personal supplementation routine, not an established medical protocol or recommended dosage for everyone. Double Wood offers both NMN and Trans-Resveratrol separately, allowing each supplement to be dosed independently.

NAD (Nicotinamide Adenine Dinucleotide) is a vital coenzyme involved in energy production, DNA repair, and cell metabolism. NMN (Nicotinamide Mononucleotide) and NR (Nicotinamide Riboside) are both precursors to NAD+, meaning they are converted into NAD in the body to help boost its levels. NMNH (Nicotinamide Mononucleotide Hydrochloride) is a specific form of NMN thought to elevate NAD+ levels and sustain them longer with a enhanced stability compared to regular NMN. While NMN and NR both increase NAD+ levels, they differ in their chemical structures and the pathways by which they are converted to NAD.

Nicotinamide Mononucleotide (NMN) is a naturally occurring compound that serves as a direct precursor to nicotinamide adenine dinucleotide (NAD+), a coenzyme required for cellular energy production, DNA repair, mitochondrial function, and the activity of sirtuins—proteins involved in healthy aging.

Research has shown that NAD+ levels naturally decline with age, and this decline is associated with reduced cellular energy production and changes in metabolic function. As NAD+ becomes less available, cells may become less efficient at maintaining normal repair and energy-generating processes.

Supplementing with NMN provides the body with a building block used to produce NAD+. Clinical studies have shown that oral NMN supplementation can increase NAD+ levels in humans, making it an area of growing interest for supporting healthy aging, cellular energy, cognitive health, and metabolic function.

Yes. Every batch is third-party tested by an ISO/IEC 17025-accredited laboratory for identity, NMN purity, heavy metals, and microbial safety. ?-NMN (the bioactive beta isomer) is verified by HPLC against reference standards — the industry-standard method for distinguishing ?-NMN from degradation products and the alpha isomer. The full COA panel also covers four heavy metals via ICP-MS (arsenic, cadmium, lead, mercury against USP <2232> limits) and six microbial screens (Total Plate Count, Yeast & Mold, Coliform, E. coli, Salmonella, Staphylococcus aureus per USP <2021>/<2022> and AOAC methods). Manufactured in a cGMP-certified U.S. facility.

The COA verifies 250 mg of ?-NMN per capsule by HPLC, with the active assay confirming purity at ?99% — the de facto category standard for premium NMN. Identity is confirmed against the ?-NMN reference standard, distinguishing the bioactive beta isomer from the inactive alpha form. Heavy metals: arsenic, cadmium, lead, and mercury verified below USP <2232> daily-intake limits via ICP-MS. Microbial counts within USP and AOAC specifications. The product is shelf-stable at room temperature; no refrigeration is required. The current batch COA is linked above for verification against the lot number on your bottle.