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TUDCA Supplement

$ 27.95

A water-soluble bile acid studied for its role in liver wellness and healthy bile flow.* 99%+ purity tested. Every batch tested for purity, potency, heavy metals, and microbial safety. Third-party tests by ISO/IEC 17025 accredited labs. COAs published openly.
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Description

TUDCA (Tauroursodeoxycholic Acid) is a water-soluble bile acid naturally produced in small amounts in the body and used in traditional Chinese medicine for centuries.

Double Wood's TUDCA is fully synthetic, manufactured in a lab rather than derived from bear bile or any other animal source. This delivers the same well-studied molecule without the ethical sourcing concerns associated with traditional bile acid extraction. TUDCA supports bile acid balance and digestive flow, supporting healthy bile flow from the liver to the intestines.*

This is a targeted, mechanistically specific ingredient compared to most general "liver support" supplements. Double Wood's TUDCA delivers 500mg per serving at 99%+ purity. Every batch is tested for purity, potency, heavy metals, and microbial safety- third-party tests are conducted by ISO/IEC 17025-accredited labs. COAs are published openly. As part of an overall wellness regimen, TUDCA pairs well with NAC, which supports glutathione pathways and cellular antioxidant defenses, and Milk Thistle, which provides complementary antioxidant support for liver cells.*

Soy-Free, Gluten-Free, Non-GMO

Benefits
  • 99%+ purity tested TUDCA, a well-studied bile acid supplement verified every batch
  • Supports liver health and bile acid balance as part of a targeted daily liver wellness regimen*
  • Supports healthy bile flow from the liver to the intestines as part of broader digestive wellness*
  • Every batch tested for purity, potency, heavy metals, and microbial safety. Third-party tests by ISO/IEC 17025 accredited labs. COAs published openly.
  • Gluten-Free, Soy-Free, Non-GMO – manufactured in a cGMP-certified U.S. facility

Directions & Dosage

Take 2 capsules (500mg) per day on an empty stomach, or split into one capsule morning and one evening for steadier bile-flow support. Do not exceed 4 capsules per day.

The Science Behind Tauroursodeoxycholic Acid (TUDCA)

Bile acid balance and liver wellness. Bile acids play a central role in digestion and liver function — they are synthesized in the liver, stored in the gallbladder, and released into the small intestine to support fat digestion and nutrient absorption. TUDCA, as a water-soluble bile acid, has been studied for its role in supporting healthy bile composition and flow, which is foundational to broader liver and digestive system wellness.*

Research context. TUDCA has been the subject of clinical and preclinical research across a range of liver-related applications. A review published in Nature Clinical Practice Gastroenterology & Hepatology (Beuers U, 2006) explored TUDCA's mechanisms in supporting liver cell integrity and bile flow. Research has also examined TUDCA's role in supporting the endoplasmic reticulum stress response — a cellular pathway relevant to liver cell wellness under metabolic load.*

A well-studied liver and digestive complement. TUDCA is a well-researched bile acid supplement. For those building a liver wellness regimen, the combination of TUDCA for bile flow support, NAC for glutathione and cellular antioxidant pathways, and Milk Thistle for complementary liver antioxidant support represents a well-rounded approach.*

View Latest Certificate of Analysis

Lot-specific COA

Certificate of Analysis

Meets Listed Specifications
Product Name
TUDCA Supplement
Lot Number
2612000
Manufacturing Date
08/2026
Expiration Date
08/2028
Test Specification Result
Capsule Weight 338-392 mg 365 mg
DIETARY INGREDIENTS
Tauroursodeoxycholic Acid 450-550 mg 497.22 mg
Disintegration
Disintegration Time: NMT 30 Minutes Passed
HEAVY METALS
Arsenic (As) ICP<10 µg/serving 0.066µg/serving
Cadmium (Cd) ICP<4.1 µg/serving 0.000 µg/serving
Lead (Pb) ICP<0.5 µg/serving 0.058 µg/serving
Mercury (Hg) ICP<0.3 µg/serving <0.000 µg/serving
MICROBIAL
Total Plate Count <10,000 CFU/g <190 CFU/g
Total Yeast & Mold Count <1000 CFU/g <19 CFU/g
E.Coli Absent Absent
Salmonella spp. Absent Absent
Staphylococcus aureus Absent Absent

Results apply only to the lot shown on this certificate.

View Third Party Test Results
Identity, potency, and contaminants verified per batch Identity, potency, and contaminants verified per batch
Manufactured in an FDA-registered cGMP facility Manufactured in an FDA-registered cGMP facility
Manufactured in the USA from Globally Sourced Materials Manufactured in the USA from Globally Sourced Materials

Benefits

  • Bile Salt for Liver Health - TUDCA is considered a liver supplement since it supports healthy levels of liver enzymes
  • Bile Salt for Gallbladder Health - Studies show TUDCA may help optimize the content of gallbladder bile
  • Other Health Benefits - TUDCA is most known for liver health but also supports intestinal, immune, gallbladder, and thyroid health
Benefits

Tauroursodeoxycholic Acid (TUDCA)

Tauroursodeoxycholic acid is a naturally occurring water-soluble bile acid formed by the conjugation of taurine with ursodeoxycholic acid (UDCA). Taurine conjugation is associated with water solubility and is the form the body naturally produces.

As a supplement, TUDCA has been studied for its potential to support liver health, healthy bile flow, and digestive function.* Double Wood's formula delivers 500mg per 2-capsule serving at 99%+ purity. Every batch is tested for purity, potency, heavy metals, and microbial safety. Third-party tests are conducted by ISO/IEC 17025-accredited labs. COAs are published openly.

Tauroursodeoxycholic Acid (TUDCA)

What Customers Are Saying

Reviews

"Keeping customers informed about their delivery and being proactive in reaching out to customers. Excellent customer service. It's obvious you're in the business of caring for people. Thank you!"

Sonia B.

"Very pleased with the service, from placing my order to receiving it. Painless, simple, and quick."

Craig V.

"Doublewood has consistent quality shipping, great product introductions, and tracks previous orders, and provides incentives for frequent customers. Products are single ingredient supplements, for optimal dosage. Great source for unique supplements."

John T.

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Supplement Facts

Pairs well with

Powerful alone, stronger together. TUDCA Supplement delivers targeted support on its own, but combining it with complementary ingredients can help create a more holistic and balanced approach to wellness.

  • N-Acetyl Cysteine (NAC) Supplement

    N-Acetyl Cysteine (NAC) boosts your body's antioxidant levels, supporting overall wellness and enhancing your natural defenses.

  • Liposomal Glutathione Supplement

    Liposomal Glutathione offers enhanced absorption for powerful antioxidant support, helping maintain your body's natural levels effectively.

Frequently Asked Questions

What exactly is TUDCA and why is it different from other liver supplements?

Most liver supplements work through antioxidant pathways, supporting the liver's defenses against oxidative stress. TUDCA works differently. It is a water-soluble bile acid that supports healthy bile acid balance and bile flow, the process by which the liver moves bile through the biliary system to the intestines. This is a targeted, mechanistically specific ingredient compared to most liver supplements, which is why TUDCA has attracted research interest among those building liver wellness routines.*

Can I take TUDCA if I don't have a gallbladder?

Yes. Without a gallbladder, bile flows continuously into the small intestine rather than being stored and released with meals, which can make fat digestion more challenging for some people. Many people who have had their gallbladder removed take TUDCA as part of an ongoing daily routine, following the standard directions of 2 capsules daily on an empty stomach.* This is a common reason people use TUDCA long-term.

What is the difference between TUDCA and UDCA?

UDCA (ursodeoxycholic acid) is a well-researched bile acid with an extensive clinical history. TUDCA is UDCA conjugated with taurine, which makes it water-soluble and is the form the body naturally produces. Taurine conjugation is associated with water solubility.

How should I take TUDCA and when?

Take 2 capsules (500mg) per day on an empty stomach. Many people working with higher daily amounts split dosing across the day. The standard research-referenced range is 500–1,000mg daily. Do not exceed 4 capsules per day. Taking it on an empty stomach is recommended, as it may improve absorption and minimize the risk of digestive discomfort.

What supplements pair well with TUDCA?

TUDCA pairs well with NAC and Milk Thistle for a more complete liver wellness regimen. NAC supports the body's glutathione pathways, the primary cellular antioxidant defense system, while Milk Thistle provides complementary antioxidant support for liver cells. TUDCA addresses bile flow and the digestive aspects of liver wellness, while NAC and Milk Thistle address the antioxidant and cellular protection aspects. Together, they cover the liver wellness story from multiple angles.* TUDCA also pairs well with Colostrum for those who want combined liver and gut wellness support.

Is TUDCA safe to take daily?

TUDCA is generally well tolerated at recommended serving sizes and has been used in research settings at a range of doses. As with any supplement targeting a specific organ system, those managing liver conditions, gallbladder issues, or taking prescription medications — particularly those metabolized by the liver — should speak with their healthcare provider before starting TUDCA. For healthy adults building a liver wellness routine, it is widely used as a consistent daily supplement.

How is Double Wood's TUDCA tested and what does 99%+ purity mean?

The 99%+ purity designation refers to the TUDCA compound itself, meaning the active ingredient is at least 99% pure with minimal extraneous compounds. The Certificate of Analysis is publicly available on this page with no request needed.

Overall rating: 4.8508773 / 5 from 228 reviews.

AI Generated Review Summary

TUDCA Supplement is highly regarded for its effectiveness in enhancing liver health and providing neuroprotective benefits. Customers appreciate its fast shipping, excellent value, and high-quality formulation. The supplement is also praised for its ability to alleviate gallbladder problems and bile sludge, with many users reporting feeling better each day.

Summary topics

  • Shipping Speed (7%): It was observed by customers that the shipping was fast and prompt, with multiple mentions of "fast shipping" and "fast delivery."
  • Price Value (6%): Customers appreciated the great prices offered by Doublewood for the product at a great price. (100% agreement)
  • Value for Money (6%): It was observed by customers that the product offers excellent value for money and is highly recommended.
  • Effectiveness (4%): It was highlighted by customers that Tudca works well for them and they are satisfied with its effectiveness.

Review topics: ["feeling","packaging","quality","issues","value","pain","results","shipping","improvement","price","supplement","tudca","service","work","medication","wood","order","effect","deal","liver","help","health","enzymes","difference","doctor","life","brand","digestion","use","addition"].

Review highlights

  • "Excellent value - fast efficient dispatch and delivery :)" — Jen
  • "Great quality product. Fast shipping." — Sadie
  • "Good quality, great price." — Pamela

Reviews

Tudca

"Have not been on it long enough to claim big results however I have experienced more energy. Plan to continue supplementing with this product"

— Paulina V. (5/5)

"They sent the wrong product."

— Bill (1/5)

"Got here super quick!"

— JD (4/5)

"very useful 👌"

— julia (5/5)

Amazing

"Great company, clean an trustworthy supplements. Highly recommend."

— Nelly S. (5/5)

Tudca’s a major bile and

"Tudca’s a major bile and butyrate supporter; I notice tudca helps motility as well. Excellent product"

— Kathrina O. (5/5)

"Ok"

— Terronie (5/5)

"Double woods products are always high standard and their purity is without question product works and presents as claimed good company to buy from"

— Kenneth (3/5)

Great help

"This supplement was a great help with my very overwhelmed liver. I don't know what I would've done without it. I could see the difference after the first dose. I like the Double Wood brand, the supplements are good quality with no bad additives."

— Eva P. (5/5)

"Doublewood is top tier. One of 3 site i buy from"

— Gilbert (5/5)

Q&A

Can this or the other liver support products on your site be taken if the gallbladder has been removed?
Thank you for your question regarding the use of TUDCA (Tauroursodeoxycholic Acid) after gallbladder removal. Yes, TUDCA can generally be taken even if your gallbladder has been removed. TUDCA is a bile acid that helps promote healthy bile flow and supports liver and digestive health, which can be beneficial for individuals without a gallbladder. Since the gallbladder&#x27;s role in bile storage is bypassed, TUDCA can assist in maintaining bile flow directly from the liver to the small intestine, which may help with fat digestion and overall liver function. However, as with any supplement, we recommend consulting with your healthcare provider before starting TUDCA, especially if you have specific health concerns or are on other medications.
what does it do for galbladder
TUDCA (Tauroursodeoxycholic acid) is beneficial for the gallbladder due to its ability to support bile flow and reduce the formation of gallstones. Here’s how it helps: Promotes healthy bile flow: TUDCA aids in the production and secretion of bile, which helps the gallbladder properly digest fats and prevents bile from becoming too concentrated, reducing the risk of gallstone formation. Prevents bile acid buildup: TUDCA helps break down and reduce toxic bile acids, protecting liver and gallbladder cells from damage. Reduces inflammation: It has anti-inflammatory properties that can support gallbladder and liver health by preventing or reducing inflammation of these organs. Aids in dissolving gallstones: TUDCA can help dissolve small cholesterol-based gallstones, potentially avoiding the need for surgical intervention. These properties make TUDCA a helpful supplement for gallbladder health, especially for those with impaired bile flow or a history of gallstone issues. Always consult a healthcare provider before use.
What&#x27;s the gelatin derived from?
Our gelatin is bovine.
How and from where is your tudca sourced?
Our synthetic TUDCA is produced through a series of chemical reactions starting from cholic acid, which is converted to UDCA and then conjugated with taurine. The process involves careful control of reaction conditions and purification steps to ensure the final product is of high purity and quality. This synthetic production method allows for the consistent and scalable manufacture of TUDCA for use in dietary supplements and therapeutic applications. The raw material is sourced in China. We hope this helps.
Do you derive this from Ox Bile?
Historically, ursodeoxycholic acid (UDCA) was first discovered in the bile of bears. Bears naturally produce a significant amount of UDCA, which was used in traditional Chinese medicine for its health benefits. However, the use of bear bile has raised significant ethical and conservation concerns due to the inhumane treatment of bears and the impact on bear populations. For this reason, our TUDCA is synthetically made. We do offer a separate Ox Bile supplement as well if this is your preference. Ox Bile is also used to aid in the digestion of fats. We hope this helps!

TUDCA Supplement

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$ 27.95

Primary Benefit

Liver Health

Other Benefits

Product Form

Capsule
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