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Turkey Tail Mushroom Supplements: Benefits, Side Effects, and More

Turkey Tail Mushroom Supplements: Benefits, Side Effects, and More

Jessica Justh  |

Let’s Meet the Turkey Tail Mushroom

The Turkey Tail Mushroom (Trametes versicolor) is one of the most recognizable medicinal fungi in the natural world. Its name comes from its striking appearance — thin, fan-shaped layers with multicolored rings that resemble a wild turkey’s tail feathers. These rings often display hues of brown, gray, white, and even blue or red, creating a visually captivating pattern.

Commonly found on decaying logs, stumps, and trees in forests across North America, Europe, and Asia, this resilient fungus thrives in a variety of climates. Turkey Tail is a saprophytic mushroom, meaning it feeds on decomposing wood, playing a crucial role in breaking down organic material in the ecosystem. Its ability to adapt to various environmental conditions and its rich history of use in traditional medicine makes it a popular choice in wellness and herbal remedies.

Historically, Turkey Tail mushrooms have been used in ancient practices for their health-promoting properties. Today, scientists continue to study the mushroom’s potential therapeutic effects, especially in supporting immune function and promoting overall well-being.(1) Beyond its aesthetic appeal, the Turkey Tail mushroom has captured the attention of researchers and herbalists alike for its unique composition of natural compounds.

Turkey Tail and Eastern Herbal Practices

Turkey Tail has been deeply rooted in Eastern herbal medicine traditions for centuries, particularly in Traditional Chinese Medicine (TCM) and Japanese Kampo medicine. Known as "Yun Zhi" in China and "Kawaratake" in Japan, this mushroom has long been recognized for its health-supporting properties.

In Traditional Chinese Medicine, Turkey Tail is believed to tonify Qi — the vital energy that flows through the body. It has been used in TCM practices to support the lungs, liver, and spleen, and TCM practitioners have valued Turkey Tail for its potential role in supporting healthy digestion and promoting vitality and resilience. 

In Japan, Turkey Tail, or Kawaratake, has been studied extensively for its unique natural compounds. The mushroom extract derived from Turkey Tail, known as PSK (polysaccharide K), has been incorporated into certain modern healthcare practices in Japan. Ongoing research on PSK continues to explore it as a complementary approach in cancer-related research.(2) Studies also suggest that Turkey Tail extract may support immune health, including in contexts where immunity is compromised.(3) 

In Chinese and Japanese traditions, Turkey Tail has historically been used to support a healthy inflammation response, gut health, and overall vitality and wellness. These traditional practices have inspired modern research exploring the mushroom’s potential role in promoting immune health and general well-being. 

What is a Turkey Tail Supplement?

Turkey Tail supplements offer a convenient way to incorporate this traditional mushroom into modern wellness routines. They are typically made from either the fruiting body (the visible part of the mushroom) or the mycelium (the underground network of fungal threads). 

These supplements are available in various forms, including capsules, powders, and liquid extracts. They can be taken on their own or combined with other mushrooms like Reishi or Chaga as part of a balanced approach to overall wellness. 

Turkey Tail’s Bioactive Compounds

The potential health-supporting properties of Turkey Tail mushrooms are believed to stem from several bioactive compounds, including:

Bioactive Compound

Primary Benefits

Polysaccharopeptides (PSK & PSP)

  • Immune system support 
  • Adjunct to standard cancer therapy

Beta-Glucans

  • Immune system support
  • Promotes cardiovascular health4
  • Helps to maintain normal metabolic function (5)

Phenolic & Flavonoid Compounds

  • Antioxidant support6
  • Cellular health support6
  • Promotes a normal inflammatory response (6)

Prebiotics

  • Gut and digestive health support (7)
  • Immune system support (8)

Let’s dive into each bioactive compound, starting with polysaccharopeptides:

Polysaccharopeptides (PSK & PSP)

Polysaccharopeptides, particularly PSK (Polysaccharide Krestin) and PSP (Polysaccharide Peptide), are among the most researched compounds in Turkey Tail mushrooms. These molecules are being studied for their potential to support immune function and overall health. This may interest individuals with varying health concerns, including those with immune system challenges or those recovering from certain illnesses. 

  • PSK (Polysaccharide Krestin) has been widely studied in Japan as a complementary approach to cancer research. It is believed to help the body maintain immune function, particularly in individuals undergoing certain treatments, such as chemotherapy or radiation.
  • PSP (Polysaccharide Peptide), primarily studied in China, is also being researched for its potential to support immune function. PSP may influence the production of certain proteins that help regulate the immune system and maintain a balanced inflammatory response, making Turkey Tail a supplement of interest for supporting overall immune health and resilience. 

Beta-Glucans: Polysaccharides Supporting Immune and Overall Health

Beta-glucans are naturally occurring polysaccharides found in the cell walls of mushrooms, including Turkey Tail. These compounds are studied for their potential role in supporting the body’s immune system.

Specifically, beta-glucans interact with immune receptors on white blood cells, such as macrophages and dendritic cells, which are involved in the body’s immune response. By doing so, beta-glucans may help support the body’s natural ability to respond to infections and illnesses.

Beyond supporting immune health, beta-glucans may also have a potential role in: 

  • Helping to support healthy cholesterol levels by binding to bile acids in the digestive system.
  • Contributing to cardiovascular health by supporting a normal inflammatory response in the blood vessels.
  • Promoting metabolic health by supporting healthy blood sugar and insulin sensitivity.

Phenolic and Flavonoid Compounds: Potent Antioxidants

Turkey Tail mushrooms contain a variety of phenolic and flavonoid compounds, which are studied for their antioxidant properties. These compounds help neutralize free radicals, which are unstable molecules that may contribute to oxidative stress. Oxidative stress has been associated with aging and certain health conditions.(9) 

The phenolic and flavonoid compounds in Turkey Tail mushrooms may support overall well-being by:

  • Helping to support cells from oxidative stress. 
  • Supporting a healthy inflammatory response. 
  • Supporting brain health by protecting cells 
  • Contributing to heart health by supporting healthy LCL levels. 

Prebiotics: Supporting Gut Health and Digestion

One of the lesser-known characteristics of Turkey Tail mushrooms is that they contain fiber that may support a healthy balance of gut bacteria. This fiber serves as a food source for probiotics, or “good bacteria,” that reside in the gut. Maintaining a healthy balance of gut bacteria is important for digestive health, immune function, and overall well-being.

The fiber in Turkey Tail may help support the growth of Bifidobacterium and Lactobacillus, two types of beneficial bacteria. These bacteria help to:

  • Support natural digestive functions by assisting in the breakdown of food. 
  • Support the gut lining, contributing to overall digestive health. 
  • Promote immune health, as a significant portion of the immune system is associated with the gut. (10)

Turkey Tail Health Benefits

Turkey Tail mushrooms play a potential role in supporting overall health and wellness. As explored above, the bioactive compounds these mushrooms contain have been studied for various benefits, summarized below: 

  • Immune System Support: Turkey Tail is recognized for its potential to support the immune system by influencing immune cell activity.
  • Gut Health: Turkey Tail mushrooms contain prebiotic fibers that support the growth of beneficial gut bacteria, contributing to digestive health.
  • Antioxidant Support: The antioxidants in Turkey Tail may help protect cells from oxidative stress caused by free radicals, supporting overall health.
  • Liver Support: Some studies suggest that Turkey Tail may support liver health by protecting against oxidative stress and potential damage.(11)
  • Potential Antiviral Support: Some studies have examined Turkey Tail’s potential role in supporting the body’s natural defense. 

Support A Healthy Lifestyle With Double Wood Supplements

Individuals who are seeking a natural supplement that offers immune system support and aids in digestion can consider Double Wood Supplement’s Turkey Tail Mushroom capsules. Carefully crafted with pure and potent ingredients and backed by rigorous third-party testing, Double Wood Supplements can help support your wellness journey. 

Visit Double Wood Supplements to learn more about how our supplements can help you achieve your wellness goals.

Turkey Tail Frequently Asked Questions (FAQs)

1. Are there any side effects when taking Turkey Tail supplements?

Turkey Tail supplements are generally considered safe, but some users may experience side effects such as digestive issues, darkened stools, or darkened nail pigmentation.

2. Is Turkey Tail safe for everyone?

Turkey Tail supplements are considered safe for most people. However, they are not recommended for people with mushroom or mold allergies. Pregnant or breastfeeding women should consult with a medical professional before taking any new supplements.

3. How does Turkey Tail interact with other medications?

Turkey Tail may interact with immunosuppressants or blood thinners. Consult with your healthcare provider if you want to start taking Turkey Tail supplements while on other medications. 

4. What forms of Turkey Tail supplements are available?

Turkey Tail supplements are available in a few different forms, including capsules, powders, and liquid extracts. 

5. How long does it take to see the effects of Turkey Tail supplementation?

The effects of Turkey Tail supplements will vary by individual. With regular supplementation, some users may notice changes in a few weeks, while others may not notice an impact for a few months. 

6. Are there quality concerns with Turkey Tail supplements?

The quality of Turkey Tail supplements can vary between products. It’s best to look for purified supplements or dried mushrooms from reputable sources. Ideally, find a product that has gone through third-party testing to validate its quality and purity.

7. Can Turkey Tail be used alongside conventional cancer treatments?

Turkey Tail supplements are not a replacement for conventional cancer treatments, though they may be used alongside doctor-recommended therapies. Please consult with an oncologist before starting Turkey Tail supplements. 

Citations:

[1] https://www.sciencedirect.com/science/article/pii/S2214799324000699 

[2] https://www.cancer.gov/about-cancer/treatment/cam/hp/mushrooms-pdq 

[3] https://pmc.ncbi.nlm.nih.gov/articles/PMC6889544/ 

[4] https://pmc.ncbi.nlm.nih.gov/articles/PMC5810204/ 

[5] https://pmc.ncbi.nlm.nih.gov/articles/PMC7770584/ 

[6] https://pmc.ncbi.nlm.nih.gov/articles/PMC6165118/ 

[7] https://pmc.ncbi.nlm.nih.gov/articles/PMC11084426/ 

[8] https://pubmed.ncbi.nlm.nih.gov/32996638/ 

[9] https://pubmed.ncbi.nlm.nih.gov/31960481/ 

[10] https://pmc.ncbi.nlm.nih.gov/articles/PMC8001875/ 

[11] https://pmc.ncbi.nlm.nih.gov/articles/PMC6270077/