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What is Serrapeptase?

Serrapeptase

Jessica Justh  |

Serrapeptase is a proteolytic enzyme that helps break down proteins into smaller components. Originally discovered in the digestive system of silkworms, where it plays a role in cocoon dissolution, it is now commercially produced through bacterial fermentation. 

While primarily used as a dietary supplement, Serrapeptase has been studied for its potential role in supporting sinus health, joint function, and post-surgical recovery.(1) It is believed to break down non-living tissue while leaving healthy cells intact. However, more research is needed to fully understand its effects and safety on human health. 

What is Serrapeptase Good For? History of Use

Proteolytic enzymes like Serrapeptase have been used and researched for decades. First introduced in Japan and Europe, Serrapeptase has been explored for its potential role in breaking down proteins and supporting tissue health.  

Historically, physicians believed Serrapeptase to have an effect on respiratory health and recovery post-surgery. (2, 3) Over time, its use as a dietary supplement has spread worldwide, with users reporting potential support for pain management, the natural healing process, and cardiovascular health. (1)  

Potential Serrapeptase Benefits

While research on Serrapeptase is ongoing, preliminary studies and anecdotal evidence suggest a variety of potential health benefits. These include:

1. Role in Inflammation and Recovery

Serrapeptase may support the body’s natural inflammatory response and comfort levels by helping break down proteins and non-living tissue in the body. Research has explored its potential effects on:

  • Joint Health: May play a role in supporting normal inflammatory responses in joints (4)
  • Nerve Health: Research has explored its effects on soft tissue and nervous system support
  • Postoperative Support: It has been studied for its potential to promote a healthy recovery process (5)

2. Respiratory Support

Again, this enzyme has been studied for its role in protein breakdown, including non-living tissue like mucus. Thus, it may offer the following support for those dealing with respiratory conditions: 

  • Sinus Health: May help support normal mucus clearance from nasal passages (6)
  • Lung Function: Has been investigated for its role in maintaining healthy airways (6)
  • Breathing Comfort: May have a potential effect on overall respiratory wellness (6) 

3. Support for Post-Surgical and Injury Recovery

One of the potential applications of Serrapeptase is supporting the body’s natural healing process after an injury or operation. This is because the enzyme may help with: 

  • Tissue Clearance: Studied for its potential support for removing non-living tissue (7)
  • Fluid Balance: Believed to play a role in maintaining normal swelling levels (5)
  • Scar Formation: May have a potential effect on healthy tissue recovery (7) 

4. Cardiovascular Health

Serrapeptase is believed to support overall cardiovascular health by:

  • Fibrin Management: May help break down non-living tissue, like fibrin in blood vessels (9)
  • Vascular Health: Explored for its effects on normal inflammatory processes within blood vessels
  • Circulatory Function: Studied for its potential role in supporting healthy blood flow
Serrapeptase Benefits

Who Should Consider Serrapeptase Supplementation?

As mentioned throughout, Serrapeptase has been studied for its potential effects on normal inflammatory processes, mucus viscosity, and tissue health. While research on its efficacy is still ongoing, certain individuals may be more drawn to exploring its potential effects. 

1. Individuals Seeking Natural Ways to Support a Healthy Inflammatory Response

  • People looking for support for joint health and mobility
  • Those recovering from injuries or surgery who want support for the body’s natural healing process
  • Individuals seeking to support overall wellness as it relates to inflammation-related concerns

2. People with Respiratory Issues

  • Individuals looking for support maintaining clear airways and healthy mucus levels
  • Those experiencing respiratory challenges due to seasonal or environmental conditions

3. Those Recovering from Surgery or Trauma

  • People undergoing postoperative recovery and want to support the body’s natural healing process
  • Athletes or individuals with minor sports injuries who want to maintain normal tissue recovery

4. Cardiovascular Health Enthusiasts

  • Individuals looking to support circulatory health by promoting healthy blood flow
  • Those interested in maintaining vascular health

Who Should Avoid Serrapeptase?

As with any new supplement, always consult with a medical professional before starting Serrapeptase. It may not be the right fit for everyone’s health and wellness needs, including: 

  • Individuals on blood thinners or anticoagulants (there may be an increased risk of excessive bleeding)
  • Pregnant or breastfeeding women
  • People with bleeding disorders (hemophilia or similar conditions)
  • Anyone undergoing surgery (typically should discontinue use at least 2 weeks before)

Potential Serrapeptase Side Effects

Although generally well-tolerated, Serrapeptase can cause some side effects, particularly in higher doses or when taken with certain medications. Common side effects include: 

  • Mild gastrointestinal discomfort (bloating, nausea, diarrhea)
  • Skin rashes or allergic reactions in sensitive individuals
  • Increased bleeding risk due to its fibrinolytic activity

What Does the Latest Research Indicate About Serrapeptase Supplementation?

Respiratory Health

A recent study suggests Serrapeptase may help support mucus clearance by influencing its viscosity. Ongoing studies continue to explore its potential role in respiratory conditions, including those infected with COVID-19. (8)  

Fibrosis and Pulmonary Health

A randomized controlled trial investigated the use of systemic enzyme supplements containing Serrapeptase in patients with idiopathic pulmonary fibrosis. The study reported improvements in certain symptoms and health-related quality of life measures, though further research is needed to fully understand its effects and safety in this population. (10)

Frequently Asked Questions (FAQs)

  1. What are some signs Serrapeptase is working?

Individual results with Serrapeptase may vary. Some users report noticing initial effects within one to four weeks, while long-term benefits may take several months.

  1. Are There Any Interactions with Other Medications?

Yes, Serrapeptase may interact with certain medications, including:

  • Blood thinners (warfarin, aspirin, heparin): May increase bleeding risk
  • NSAIDs (ibuprofen, naproxen): Potential inflammatory effects
  • Antibiotics: Some research suggests it may influence their activity

Always consult a healthcare provider before starting supplementation.

Support a Healthy Lifestyle with Double Wood Supplements

At Double Wood Supplements, we prioritize formulating high-quality, research-backed supplements to support your health. 

Our Serrapeptase supplement is formulated for optimal absorption and efficacy, offering a trusted option for those seeking natural support for inflammation respiratory health, and cardiovascular health.

Why Choose Double Wood Supplements?

  • Third-party tested for purity and potency.
  • High-quality ingredients sourced from trusted suppliers.
  • No fillers or artificial additives – just clean, effective supplements.

Explore our full range of supplements at Double Wood Supplements to support your health and wellness goals!

Note: This article is for informational purposes only and should not replace professional medical advice. Always consult with a healthcare professional before starting any new supplement or making significant changes to your health regimen.

Citations

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC7585045/  

[2] https://pubmed.ncbi.nlm.nih.gov/6366808/

[3] https://pmc.ncbi.nlm.nih.gov/articles/PMC8265778/ 

[4] https://pmc.ncbi.nlm.nih.gov/articles/PMC7032259/ 

[5] https://pubmed.ncbi.nlm.nih.gov/18272344/ 

[6] https://pubmed.ncbi.nlm.nih.gov/12911824/ 

[7] https://pmc.ncbi.nlm.nih.gov/articles/PMC5790697/ 

[8] https://pmc.ncbi.nlm.nih.gov/articles/PMC9599151/ 

[9] https://pubmed.ncbi.nlm.nih.gov/24799449/ 

[10] https://www.mdpi.com/2079-9721/12/7/155