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Magnesium L-Threonate (Magtein) Supplement

$ 30.95

Magnesium L-Threonate enhances brain magnesium levels, promoting cognitive health and helping you stay sharp and focused.
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Description

Double Wood's Magnesium L-Threonate features patented Magtein®, a specialized form of magnesium formulated to cross the blood-brain barrier and deliver magnesium directly to the brain, supporting cognitive function, deep sleep, and nervous system health. It has been studied for its role in supporting brain magnesium levels, a distinction that matters for anyone building a serious cognitive wellness or evening recovery regimen.* Each 4-capsule serving delivers 2,000mg of Magtein®, yielding 144mg of elemental magnesium, matching the dose used in the published research. Every batch is NSF Contents Certified, independently tested and audited to NSF/ANSI 173, with the Certificate of Analysis published openly on this page.

For a more intentional evening regimen, Magnesium L-Threonate pairs most naturally with Apigenin, supporting relaxation and a calm bedtime routine together. L-Theanine rounds out a three-part evening routine for those who want mental calm, nervous system support, and sleep readiness addressed in a single consistent nightly regimen.*

Soy-Free, Gluten-Free, Non-GMO

Benefits
  • Patented by design. Magtein® is the specific, clinically studied form of magnesium L-threonate used in published human research, not a generic magnesium L-threonate alternative.*
  • Built for cognitive support. Magtein® has been studied for its role in supporting memory, working memory, and mental clarity as part of a consistent daily routine.*
  • Supports deep, restorative sleep. Magnesium L-Threonate has been studied for its role in supporting healthy sleep architecture, including deep and REM sleep stages, as part of an evening routine.*
  • NSF Contents Certified, independently tested and audited to NSF/ANSI 173, with the Certificate of Analysis published openly.
  • Your evening pairing. Magnesium L-Threonate pairs naturally with Apigenin as part of an evening routine, and L-Theanine rounds out a more complete three-part wind-down for those who want it.*

Directions & Dosage

Take 4 capsules daily. Most people split the serving, 2 capsules in the morning and 2 capsules approximately 2 hours before bed. Can be taken with or without food. Those new to Magnesium L-Threonate may prefer starting with 2 capsules for the first week before increasing to the full serving.

The Science Behind Magtein® Magnesium L-Threonate

Brain magnesium and the Magtein® mechanism. A foundational 2010 animal study by Slutsky et al., published in Neuron, established the mechanism behind magnesium L-threonate, showing that increasing brain magnesium was associated with improvements in learning, working memory, and synaptic density. This research helped distinguish magnesium L-threonate from other forms and laid the groundwork for human clinical investigation.

Human research on cognitive support. A 2016 randomized, double-blind, placebo-controlled trial by Liu et al. studied Magtein® in adults aged 50 to 70 with cognitive concerns over 12 weeks, finding a statistically significant improvement in overall cognitive ability with executive function nearly restored to normal. A 2022 trial by Zhang et al., published in Nutrients, found significant gains across all five subcategories of a standardized memory test in healthy adults. A more recent 2026 randomized controlled trial by Lopresti and Smith evaluated 2,000mg of Magtein® daily in 100 adults over 6 weeks, finding improvements in overall cognition, working and episodic memory, and a 7.5-year reduction in estimated brain cognitive age.*

Why form matters. Magnesium L-threonate has been studied for its role in supporting brain magnesium levels, which is what distinguishes it within the broader magnesium category and is the reason it has become a fixture in cognitive wellness and healthy aging routines.*

View Latest Test Results

Third-party tested for quality and purity

This production lot was tested for ingredient potency, elemental magnesium, capsule weight, disintegration, heavy metals, and microbial quality.

Test Claim or Limit Result
Potency
Magnesium L-Threonate (Magtein®) 1,800–2,500 mg 2,542.4 mg
Elemental Magnesium 129.6–180 mg 162.3 mg
Physical Testing
Capsule Weight 717–753 mg 735 mg
Disintegration Not more than 30 minutes Passed
Heavy Metals
Arsenic <10 µg/serving 0.147 µg/serving
Cadmium <4.1 µg/serving 0.029 µg/serving
Lead <0.5 µg/serving 0.235 µg/serving
Mercury <0.3 µg/serving 0.059 µg/serving
Microbial Testing
Total Plate Count <10,000 CFU/g Passed
Total Yeast & Mold Count <1,000 CFU/g Passed
E. coli Absent Passed
Salmonella spp. Absent Passed
Staphylococcus aureus Absent Passed

Lot: 2532202Manufactured: 01/2025

Lab: Brand Nutraceuticals, Inc.

View Certificate of Analysis (PDF)

See the original Certificate of Analysis for complete testing details, methods, and laboratory documentation.
View Certificate of Analysis View Third Party Test Results
Identity, potency, and contaminants verified per batch Identity, potency, and contaminants verified per batch
Manufactured in an FDA-registered cGMP facility Manufactured in an FDA-registered cGMP facility
Manufactured in the USA from Globally Sourced Materials Manufactured in the USA from Globally Sourced Materials

Benefits

  • Highly Bioavailable Magnesium: Magnesium L-Threonate is uniquely formulated as a mineral chelating agent, enabling it to efficiently cross the blood-brain barrier and deliver elemental magnesium directly to the brain.
  • Supports Cognitive Health: Research demonstrates that Magnesium L-Threonate effectively increases brain magnesium levels, which is essential for maintaining and enhancing cognitive functions.
  • Enhances Sleep Quality: By promoting relaxation and supporting brain health, Magnesium L-Threonate may also contribute to healthier sleep patterns, helping you achieve more restful and rejuvenating sleep.
Benefits

Magtein® Magnesium L-Threonate

Magtein® is the patented form of magnesium L-threonate, a compound formed by binding elemental magnesium to L-threonic acid, a metabolite of vitamin C. This molecular structure is what distinguishes it from other magnesium forms and is the basis for its study in the context of brain magnesium levels and cognitive function.* Each 4-capsule serving delivers 2,000mg of Magtein® and 144mg of elemental magnesium, NSF Contents Certified, independently tested and audited to NSF/ANSI 173. COAs published openly.

Magtein® Magnesium L-Threonate

What Customers Are Saying

Reviews

"I take two capsules an hour before bedtime and it helps me fall asleep quickly and stay asleep. I won’t be without it."

Gayle D.

"Love that it crosses the blood brain barrier and is neuro protective and helps me sleep better."

Jennifer R.

"Love this product! My family takes this for relaxation and to ensure good sleep quality. Highly recommend!"

Anna N.

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Reviews
Supplement Facts

Pairs well with

Powerful alone, stronger together. Magnesium L-Threonate (Magtein) Supplement delivers targeted support on its own, but combining it with complementary ingredients can help create a more holistic and balanced approach to wellness.

  • Apigenin Supplement

    Apigenin supports overall wellness with its natural antioxidant properties, found abundantly in chamomile tea.

  • Alpha GPC Supplement

    Alpha GPC supports cognitive health by providing choline, a key nutrient for brain function and memory enhancement.

Frequently Asked Questions

What makes Magnesium L-Threonate different from other magnesium forms?

Most forms of magnesium support general body functions like muscle comfort, nerve function, and sleep readiness, all valuable in their own right. What sets Magnesium L-Threonate apart is that it has been specifically studied for its role in supporting magnesium levels in the brain. This distinction is rooted in its molecular structure, which gives it properties other magnesium forms don't share. If your goal is cognitive wellness or brain-centered support, this is the form the research points to.*

What is Magtein® and why does it matter that Double Wood uses it?

Magtein® is the patented, clinically studied form of magnesium L-threonate developed by researchers at MIT. It is the specific ingredient used in published human clinical trials, not a generic magnesium L-threonate compound. Double Wood's formula is built on Magtein®, which means you're getting the same ingredient evaluated in the research at the same serving size. This matters because not all magnesium L-threonate products use the patented form.

How should I take Magnesium L-Threonate and when?

The research-backed serving is 2,000mg daily, 4 capsules total, typically split into 2 in the morning and 2 approximately 2 hours before bed. Some people notice a calming or sedative effect and prefer taking all 4 capsules in the evening. If you're new to this supplement, starting with 2 capsules for the first week, then moving to the full serving, is a reasonable approach. It can be taken with or without food.

Can I take Magnesium L-Threonate alongside Magnesium Glycinate?

Yes, many people incorporate both into their daily regimen with distinct purposes. Magnesium Glycinate is often used in the evening for a calm nervous system and relaxation. Magnesium L-Threonate is taken for its brain-centered support, split between morning and evening.* They serve different roles and are commonly used together. If you take prescription medications or have a health condition, check with your healthcare provider first.

What does the research actually show about Magtein®?

Human clinical research on Magtein® includes a 2016 randomized, double-blind, placebo-controlled trial examining cognitive ability in adults aged 50 to 70 over 12 weeks, a 2022 trial finding gains across all five subcategories of a standardized memory test in healthy adults, and a 2026 randomized controlled trial evaluating cognitive performance and sleep quality in adults over 6 weeks. All used doses aligned with the 2,000mg serving in this product. The foundational animal research, published in Neuron in 2010, established the mechanism linking increased brain magnesium to improvements in memory and synaptic density.*

Is Double Wood's Magnesium L-Threonate third-party tested?

Every batch is NSF Contents Certified, independently tested and audited to NSF/ANSI 173. The most recent COA confirmed 2,000mg of Magtein® and 144mg of elemental magnesium per 4-capsule serving, meeting label claim. The COA is publicly available on this page.

Overall rating: 4.830832 / 5 from 733 reviews.

AI Generated Review Summary

Magnesium L-Threonate (Magtein) Supplement is highly regarded for its ability to enhance brain magnesium levels, supporting cognitive health. Customers appreciate its quality, effectiveness, and the noticeable difference it makes in blood pressure and circulation. The product is praised for its sleep-enhancing properties, excellent customer service, and fast, reliable shipping. It is also noted for its great price and soy-free, gluten-free, non-GMO formulation.

Summary topics

  • Effectiveness (4%): Customers raved about the quality and effectiveness of the products, with no negative reviews mentioned.
  • Product Quality (9%): Customers expressed satisfaction with the excellent quality of the product, which was mentioned multiple times in the reviews.
  • Noticeable Difference (4%): Customers expressed satisfaction with the noticeable difference in blood pressure and circulation after using this product.
  • Magnesium Quality (8%): Customers raved about this magnesium, stating it is the best they have ever used. However, some recommend taking a different type of magnesium.
  • Relaxation Effect (4%): Customers loved the product for its ability to make them feel relaxed and sleepy before going to bed.

Review topics: ["feeling","packaging","husband","issues","quality","results","improvement","shipping","value","dose","benefits","price","energy","stomach","ingredients","sleep","pain","impact","magnesium","supplement","service","difference","effect","work","wood","order","magnesium l-threonate","capsules","cramps","clarity"].

Review highlights

  • "Great products, outstanding support, excellent customer service, and competitive pricing!" — Feisal F.
  • "Best source of magnesium Great company and great price and service" — Anonymous
  • "Thank you for a high quality product plus fast shipping!" — Anonymous

Reviews

"Delivery was really fast I was surprised"

— Mike (5/5)

Foot and leg cramp help

"Take two a day and increased my liquid intake. Rarely have foot or leg cramps any more."

— Eliese M. (5/5)

"Quality and price"

— Jim (5/5)

"So far so good, just started it!"

— Jessica (5/5)

"So far so good, just started it."

— Jessica (5/5)

Slight improvement

"I sleep a little better and that’s hugely important. So far, no improvement on my memory… I sure hope that that will improve too!"

— Olga R. (3/5)

"Great protect!"

— Suzanne (5/5)

Health

"Product is easy to take and begins working shortly after taking."

— Ronald B. (5/5)

Great for sleep

"This is how I sleep at night!"

— Rachael F. (5/5)

"My ability to sleep through the night has improved."

— Sue (5/5)

Q&A

Why can’t I find an other ingredient list?
Magtein® is the patented form of magnesium L-threonate, a compound combining magnesium with L-threonic acid, a metabolite of vitamin C. This unique formulation is designed to enhance magnesium&#x27;s ability to cross the blood-brain barrier, thereby supporting cognitive function. As for the inactive ingredients this product also contains vegetable stearate and rice flour as excipients
Just got my order of Magnesium L-Threonate...should it be taken with a meal or on an empty stomach?
Magnesium is not fat soluble so there is no need to take it with a meal.
When is best time ti take this? Can one take in the morning? As I already take mag glycinate at bedtime.
This answer can vary based on the individual. Most of our customers take it at night, due to the sleepy side effect. Since you are already taking Magnesium Glycinate you may want to check with your Dr to determine the best time take this supplement to maximize absorbency.
Does Magnesium L. thrednate come in a Gummie?
Not at this time.
Does gelatin in your product pork or beef?
Our gelatin capsules are bovine. We hope this helps!

Magnesium L-Threonate (Magtein) Supplement

From

$ 30.95

Primary Benefit

Sleep

Other Benefits

Anxiety & Stress, Brain Health

Product Form

Capsule
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