Methylated Multivitamin

Not necessarily, but you may still prefer one. Methylated vitamins are active or bioavailable forms of key B vitamins, such as methylfolate instead of folic acid and methylcobalamin instead of cyanocobalamin. These forms can be useful for people who want a targeted methylation-support formula, even if they have not confirmed an MTHFR variant. If you already tolerate standard folic acid and basic B vitamins well, a methylated formula may simply be a preference rather than a necessity.

The only way to know whether you have an MTHFR variant is through genetic testing. Common variants include C677T and A1298C, but having a variant does not automatically mean you need a specific supplement or have a health problem. Some people also look at related biomarkers, such as homocysteine, folate, or B12 status, with their healthcare provider. If you suspect methylation issues or have a known variant, it is best to review testing and supplement choices with a qualified clinician.

No. Double Wood's Methylated Multivitamin is not designed to be a comprehensive daily multivitamin. Instead, it focuses on providing key vitamins and nutrients in their biologically active, methylated forms—including L-5-MTHF (active folate), methylcobalamin and adenosylcobalamin (active vitamin B12), pyridoxal-5-phosphate (active vitamin B6), and riboflavin-5-phosphate (active vitamin B2)—along with trimethylglycine (TMG) to support healthy methylation.

Many traditional multivitamins provide a broader range of vitamins and minerals but often use synthetic forms such as folic acid instead of methylated folate. Double Wood's formula is intended for individuals who specifically want active forms of these nutrients to support normal methylation rather than a complete vitamin-and-mineral formula.

Methylfolate, also known as L-5-MTHF or 5-methyltetrahydrofolate, is the active folate form used in methylation pathways. Folic acid is a synthetic form of folate that must be converted through several steps before the body can use it as 5-MTHF. The MTHFR enzyme is involved in this conversion process, which is why people with MTHFR variants or sensitivity to folic acid often prefer methylfolate. This formula uses L-5-MTHF instead of standard folic acid.

Double Wood’s Methylated Multivitamin is designed as a targeted methylation module, not a full-spectrum multivitamin with minerals and fat-soluble vitamins. For complete daily coverage, many customers pair it with nutrients they may already get from diet or separate supplements, such as vitamin D, magnesium, omega-3s, or a mineral formula. The right pairing depends on your diet, lab work, and goals. Avoid stacking multiple products that duplicate high amounts of B vitamins unless directed by a healthcare professional.

Yes. Every batch is third-party tested by an ISO/IEC 17025-accredited laboratory for identity, individual vitamin and mineral content, heavy metals, and microbial safety. Each methylated B-vitamin (L-methylfolate, methylcobalamin, P-5-P pyridoxal-5-phosphate, riboflavin-5-phosphate) is verified by HPLC against reference standards. The full COA panel also covers four heavy metals via ICP-MS (arsenic, cadmium, lead, mercury against USP <2232> limits) and six microbial screens (Total Plate Count, Yeast & Mold, Coliform, E. coli, Salmonella, Staphylococcus aureus per USP and AOAC methods). Manufactured in a cGMP-certified U.S. facility.

The COA verifies the label-claim mcg/mg of each methylated B-vitamin per serving — L-methylfolate (the bioactive form of folate, suitable for individuals with MTHFR variants), methylcobalamin (active B12), P-5-P (active B6), and riboflavin-5-phosphate (active B2) — all measured individually by HPLC. The full panel also confirms mineral content, heavy metals below USP <2232> limits via ICP-MS, and microbial counts within USP and AOAC specifications. The current batch COA is linked above for verification against the lot number on your bottle.