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Phosphatidylserine Supplement

$ 22.95

Phosphatidylserine is essential for brain health and cognitive function, supporting memory and focus for an energized mind.
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Description

Phosphatidylserine (PS) is a phospholipid that makes up a significant portion of brain cell membranes. It plays a structural and signaling role in brain cell communication, supports membrane fluidity, and is involved in the pathways the brain uses to manage demands placed on it by mentally intense periods.*

PS is a substantively researched cognitive supplement, with a specific body of clinical evidence behind it. Multiple randomized controlled trials have examined PS supplementation at 300mg daily and found support for memory, attention, and processing speed in healthy adults, as well as support for healthy cortisol levels already within the normal range during mentally demanding conditions.*

Double Wood's formula delivers 300mg per 2-capsule serving, with active phosphatidylserine content verified by HPLC on every batch, the same analytical method used in published clinical research and a high-confidence way to confirm PS potency in a finished product. NSF Contents Certified, independently tested and audited to NSF/ANSI 173. COAs published openly.

PS is well suited for demanding days, whether that means winding down in the evening or staying composed during a mentally intense stretch. It pairs particularly well with Quercetin for those building a broader focus and antioxidant routine, combining calm focus under stress with cellular antioxidant support.*

Benefits
  • 300mg phosphatidylserine per serving, HPLC-verified every batch — the same analytical method used in published clinical research on PS
  • Studied across multiple randomized controlled trials for memory, attention, processing speed, and healthy cortisol levels already within the normal range*
  • A brain phospholipid that supports mental composure and a healthy stress response — especially well-suited for demanding days and evening decompression*
  • NSF Contents Certified, independently tested and audited to NSF/ANSI 173, for identity, potency, heavy metals by ICP-MS, and a full microbial panel
  • COAs published openly, includes lot number verification, no request needed

Directions & Dosage

Take 2 capsules (300mg) daily with food. For evening use, take approximately 30 to 60 minutes before the time you want to begin winding down. For daytime cognitive support, the serving can be split between morning and early afternoon. Do not exceed the recommended daily serving without consulting a healthcare provider.

The Science Behind Phosphatidylserine (PS) — Soy-Derived, HPLC-Verified

The clinical research base. Phosphatidylserine has a clinical evidence base for a dietary supplement. A 2010 randomized, double-blind, placebo-controlled trial by Richter et al. published in the Journal of Clinical Biochemistry and Nutrition evaluated PS supplementation in healthy older adults over 6 months, finding improvements in memory and cognitive flexibility scores. A separate double-blind trial by Benton et al. (2001) in Nutritional Neuroscience found that 300mg daily supported memory recall and processing speed in a younger adult cohort. This evidence spans multiple age groups, contributing to PS's position as a well-studied cognitive support ingredient.*

The cortisol connection. Beyond cognitive function, PS has been studied for its relationship to healthy cortisol levels already within the normal range during mentally demanding periods. Research published in the European Journal of Clinical Pharmacology (Monteleone et al., 1992) found that PS supplementation was associated with a more moderate cortisol response to mental stress in a double-blind crossover trial. This is part of the research basis for PS's role in supporting mental composure and is why it has become a common evening supplement for those who feel mentally activated at the end of demanding days.*

Why HPLC verification matters for PS. Phosphatidylserine content in a finished supplement cannot be assumed from the raw material certificate alone. The active PS content in a capsule can degrade or vary based on processing, storage, and formulation. HPLC (high-performance liquid chromatography) verification of active PS content in the finished product is a high-confidence method used in published research to confirm the labeled 300mg is present in every capsule. Double Wood verifies PS content by HPLC on every batch. NSF Contents Certified, independently tested and audited to NSF/ANSI 173. COAs published openly.

View Latest Test Results

Third-party tested for quality and purity

This production lot was tested for ingredient potency, capsule weight, disintegration, heavy metals, and microbial quality.

Test Claim or Limit Result
Potency
Phosphatidylserine (from non-GMO soy, standardized to 20%) 54-75 mg 65.5 mg
Physical Testing
Capsule Weight 270-299 mg 284.5 mg
Disintegration Not more than 30 minutes Passed
Heavy Metals
Arsenic <10 µg/serving <0.000 µg/serving
Cadmium <4.1 µg/serving 0.002 µg/serving
Lead <0.5 µg/serving 0.138 µg/serving
Mercury <0.3 µg/serving <0.000 µg/serving
Microbial Testing
Total Plate Count <1,000 CFU/g Pass
Total Yeast & Mold Count <100 CFU/g Pass
E. coli <0.1 CFU/g Pass
Salmonella spp. <0.1 CFU/g Pass
Staphylococcus aureus <0.1 CFU/g Pass

Lot: 2520601Manufactured: 09/2025

Lab: Brand Nutraceuticals, Inc.

View Certificate of Analysis (PDF)

See the original Certificate of Analysis for complete testing details, methods, and laboratory documentation.
View Certificate of Analysis View Third Party Test Results
Identity, potency, and contaminants verified per batch Identity, potency, and contaminants verified per batch
Manufactured in an FDA-registered cGMP facility Manufactured in an FDA-registered cGMP facility
Manufactured in the USA from Globally Sourced Materials Manufactured in the USA from Globally Sourced Materials

Benefits

  • SUPPORTS MEMORY AND ATTENTION - Clinically shown to assist with memory recall and sharpen focus in healthy adults. 300mg daily dose optimized for peak results*
  • SUPPORTS OVERALL COGNITIVE HEALTH - Multiple studies have shown that Phosphatidylserine may help support attention and cognitive function in healthy adults*
  • MAY BOOST COGNITIVE PERFORMANCE -Studies have shown Phosphatidylserine supports brain health, including memory, processing speed, and focus*
Benefits

Phosphatidylserine (PS) — Soy-Derived, HPLC-Verified

Phosphatidylserine is a phospholipid belonging to the class of compounds that form cell membranes throughout the body, with its highest natural concentration in brain tissue. It plays a structural role in maintaining membrane integrity and fluidity, and a functional role in cellular signaling pathways involved in brain cell communication, stress response, and memory consolidation.* Double Wood's PS is soy-derived and standardized for active phosphatidylserine content, verified by HPLC on every batch. Each 2-capsule serving delivers 300mg, consistent with the dose used across multiple randomized controlled trials in the clinical literature.

Phosphatidylserine (PS) — Soy-Derived, HPLC-Verified

What Customers Are Saying

Reviews

"Reputation of product and overall delivery and ordering experience has always been a good experience."

Jacqueline P.

"Always fast shipping and great selection no matter what you’re looking for."

Aaron B.

"Double Wood is always my go-to for supplements. Great, effective, clean products and always at a reasonable price."

Jan W.

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Pairs well with

Powerful alone, stronger together. Phosphatidylserine Supplement delivers targeted support on its own, but combining it with complementary ingredients can help create a more holistic and balanced approach to wellness.

  • Magnesium L-Threonate (Magtein) Supplement

    Magnesium L-Threonate enhances brain magnesium levels, promoting cognitive health and helping you stay sharp and focused.

  • L-Theanine Supplement

    L-Theanine offers a natural way to promote relaxation and calmness, helping you unwind without feeling drowsy.

Frequently Asked Questions

What is phosphatidylserine and why is it relevant to brain health?

As a supplement, it has a randomized controlled trial evidence base at a specific dose, which is why it has maintained a consistent presence in cognitive and performance-focused routines for decades.*

What does the research actually show about PS at 300mg?

Multiple randomized controlled trials have examined PS at 300mg daily and found support for memory, attention, processing speed, and cognitive flexibility in healthy adults across different age groups.* The evidence base includes studies in both older adults and younger working-age adults, and 300mg is a well-referenced dose in the clinical literature. Double Wood's formula is built to this dose specifically.

When should I take phosphatidylserine and does timing matter?

Timing matters meaningfully for PS. For those using it to support evening decompression and healthy cortisol levels already within the normal range at the end of demanding days,* late afternoon or early evening is the most practical window.

What makes this PS formula different from other brands?

Two things stand out. The 300mg serving matches the dose used in published clinical research. And the active PS content is HPLC-verified in the finished product on every batch. This matters because PS content can degrade based on processing and storage conditions. Verifying potency in the finished capsule rather than relying on the raw material certificate is the same standard used in clinical research settings.

What supplements pair well with Phosphatidylserine?

The confirmed complementary pairing is Quercetin, for those building a broader focus and antioxidant routine. PS supports mental focus during stress and busy schedules, while Quercetin supports antioxidant defenses and immune health. Together, they support calm cognition during demanding periods.*

Is PS soy-derived and is that a concern?

Double Wood's phosphatidylserine is soy-derived, which is standard for the majority of PS supplements on the market. The soy-derived form is the one used in the vast majority of published clinical research on phosphatidylserine. The phospholipid extraction process removes soy proteins, which are the components responsible for most soy sensitivities. Those with known soy allergies should nonetheless consult their healthcare provider before use, as individual sensitivities vary.

Is Double Wood PS third-party tested and what does the COA confirm?

NSF Contents Certified, independently tested and audited to NSF/ANSI 173. COAs published openly. The COA confirms active phosphatidylserine content by HPLC against reference standards, identity verification, four heavy metals by ICP-MS (arsenic, cadmium, lead, mercury, all below USP limits), and a full microbial panel including E. coli, Salmonella, Staphylococcus aureus, Total Plate Count, and Yeast and Mold, and includes the lot number so you can verify your specific bottle.

Overall rating: 4.864865 / 5 from 111 reviews.

AI Generated Review Summary

Customers praise the quality and price of this Phosphatidylserine supplement, highlighting its effectiveness in improving memory and cognitive health. It is gluten-free, non-GMO, and soy-free.

Summary topics

  • Product Quality (11%): Customers raved about the awesome quality of the product, which was mentioned multiple times in the reviews.
  • Product Price (16%): Based on a significant number of customers, the prevailing opinion is that the price is great.
  • Supplement Effectiveness (11%): It was reported by customers that this supplement has helped so much and has made a difference in their ability to recall.

Review topics: [quality, value, dose, shipping, results, price, supplement, clarity, effect, capsules, service, order, difference, focus, wood, deal].

Review highlights

  • "Great quality and price!" — Anonymous
  • "on time, no hassles, excellent quality thx..." — Anonymous
  • "The quality is amazing small capsule super clean and comes in 300mg other ones are 100mg ." — Cecilia B.

Reviews

"Excelente envío gracias"

— Melecio (5/5)

I am taking Phosphatidyl because

"I am taking Phosphatidyl because it is considered to be one of several supplements expected , but not proven, to improve memory. It is impossible at this early stage to know what the supplement is contributing to my brain's performance. I cannot say my recall ability is better."

— James P. (5/5)

No Change

"No change after many months of use. Disappointing."

— Elana G. (1/5)

"Arrived in a timely manner and is as advertised."

— Richard (5/5)

The best

"Love"

— Julia D. (5/5)

Please do NOT send me

"Please do NOT send me any more of your products. I have unsubscribed several times!! thank you, Mary Jo"

— Mary E. (5/5)

Really like this product

"I’ve tried other brands and keep coming back to this one. It really does help with my cognitive ability. I’m 63 and was struggling with memory and foggy brain. This made a difference for me."

— Elizabeth G. (5/5)

Very good quality

"This product is very good quality."

— irina k. (5/5)

DOUBLEWOOD

"SHIPPED AND ARRIVED QUICK"

— GORDON D. (5/5)

Great!

"Got this for my daughter."

— Mary M. (5/5)

Q&A

can you or should you take more than 300mg a day.
Thank you for reaching out with your question! For faster assistance with product-related inquiries, we recommend contacting our customer service team directly at hello@doublewoodsupplements.com. Our team will be happy to provide the information or support you need.

Phosphatidylserine Supplement

From

$ 22.95

Primary Benefit

Brain Health

Other Benefits

Anxiety & Stress, Focus & Energy

Product Form

Capsule
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