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NAD+ Supplement

$ 39.95

NAD supports your body's natural processes, promoting overall vitality as you age. Keep your energy levels balanced with this essential supplement.
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Description

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every living cell, involved in normal cellular energy metabolism.* NAD levels naturally decline with age. This doesn't mean NAD+ supplements treat or prevent age-related disease, but it's part of why NAD+ and its precursor nutrients have become an area of ongoing research interest.

Double Wood's NAD+ Supplement provides 500mg of NAD+ per serving, verified at greater than 95% purity, as the single active ingredient, not a precursor relabeled as NAD+, and not a small amount diluted inside a larger blend. We state the number plainly so you can compare labels honestly.

It's worth being transparent about where the current science stands: the strongest human clinical evidence in this category exists for precursor compounds like NMN and NR, which have been evaluated in more randomized human trials to date. Direct oral NAD+ supplementation, the approach this product uses, has less clinical trial data available so far.

Compare this formula with NMN, NMNH, or NR Malate to find the option that best fits your routine.

Soy-Free, Gluten-Free, Non-GMO, Vegan. Every batch tested. Third-party tests by ISO/IEC 17025 accredited labs. COAs published openly.

Benefits
  • Real, single-ingredient NAD+. Each serving delivers 500mg of NAD+ at 95% purity as the sole active ingredient, not diluted inside a larger blend.*
  • Supports NAD levels already within the normal range as part of a healthy lifestyle.*
  • NAD+ directly, not a precursor. NMN and NR are precursor nutrients the body converts into NAD+. This product provides NAD+ itself, a different approach than precursor-based products.
  • Currently, the strongest human clinical evidence in this category exists for precursor compounds. We think that's worth knowing so you can choose with accurate expectations.
  • Every batch tested. Third-party tests by ISO/IEC 17025 accredited labs. COAs published openly.

Directions & Dosage

Take 2 capsules (500mg) daily on an empty stomach, preferably in the morning. Do not exceed the recommended serving unless directed by a healthcare professional.

The Science Behind NAD+ (Nicotinamide Adenine Dinucleotide)

What NAD+ does in the body

NAD+ functions as an electron carrier in the biochemical reactions that convert nutrients into cellular energy, supporting normal cellular function.* NAD+ levels decline progressively with age, and researchers have examined this decline in relation to metabolic function and cellular health (Bhasin et al., Endocrine Reviews, 2023). These are NAD+'s general biological roles in the body; this doesn't mean oral NAD+ supplementation produces these specific outcomes in humans.

NAD+ versus precursor compounds, an honest comparison

It's important to understand the distinction between direct NAD+ supplementation and precursor supplementation. Most products in this category contain NMN or NR, compounds the body converts into NAD+ through several steps. A 2023 review by Freeberg et al., published in the Journals of Gerontology: Series A, examined the human clinical trial evidence for these precursor compounds and found a growing but still developing body of research, with the authors themselves describing the overall clinical picture as still unclear.

Direct oral NAD+ supplementation, the approach used in this product, is a newer strategy with even less human clinical trial data currently available than the precursor compounds. We think it's more useful to tell you honestly where the research stands than to overstate what's currently known.

View Latest Test Results

Third-party tested for quality and purity

This production lot was tested for NAD potency and identity, capsule weight, heavy metals, and microbial quality

Test Claim or Limit Result
Potency
NAD (Nicotinamide Adenine Dinucleotide) 450-550 mg 490 mg
Identity Testing
Identification Sample retention time corresponds to standard Conforms
Physical Testing
Capsule Weight 415-483 mg 449 mg
Heavy Metals
Arsenic (As) <1.5 ppm <0.000 ppm
Cadmium (Cd) <0.5 ppm 0.022 ppm
Lead (Pb) <1.0 ppm 0.254 ppm
Mercury (Hg) <0.2 ppm <0.000 ppm
Microbial Testing
Total Plate Count <10,000 cfu/g <10,000 cfu/g
Total Yeast & Mold Count <1,000 cfu/g <1,000 cfu/g
E. Coli <0.1 cfu/g <0.1 cfu/g
Salmonella spp. <0.1 cfu/g <0.1 cfu/g
Staphylococcus aureus <0.1 cfu/g <0.1 cfu/g

Lot: 2430504Manufactured: 11/2024

Lab: Brand Nutraceuticals, Inc.

View Certificate of Analysis (PDF)

See the original Certificate of Analysis for complete testing details, methods, and laboratory documentation.
View Certificate of Analysis View Third Party Test Results
Identity, potency, and contaminants verified per batch Identity, potency, and contaminants verified per batch
Manufactured in an FDA-registered cGMP facility Manufactured in an FDA-registered cGMP facility
Manufactured in the USA from Globally Sourced Materials Manufactured in the USA from Globally Sourced Materials

Benefits

  • NAD Booster- Supplementing with 95% pure NAD may help boost NAD levels as we age making is an ideal longevity supplement
  • What is NAD? - NAD is an essential Coenzyme found in all living cells. It is involved in many fundamental biological processes such as cell metabolism
  • NAD+ Levels Fall as We Age - Research shows that NAD+ concentrations decline with age across multiple tissues, with aged tissue studies reporting decreases ranging from about 10–50% in liver and 15–65% in skeletal muscle (McReynolds, Chellappa & Baur). Because NAD+ plays an important role in cellular energy metabolism, mitochondrial function, and NAD+-dependent enzymes, maintaining healthy NAD+ metabolism has become a major focus in healthy-aging research.

Benefits

NAD+ (Nicotinamide Adenine Dinucleotide)

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell, involved in cellular energy metabolism and other fundamental biological processes.* Double Wood's formula provides NAD+ directly, verified at greater than 95% purity, as the single active ingredient. Each 2-capsule serving delivers 500mg. Every batch tested. Third-party tests by ISO/IEC 17025 accredited labs. COAs published openly.

NAD+ (Nicotinamide Adenine Dinucleotide)

What Customers Are Saying

Reviews

"Reputation of product and overall delivery and ordering experience has always been a good experience."

Jacqueline P.

"Always fast shipping and great selection no matter what you’re looking for."

Aaron B.

"Double Wood is always my go-to for supplements. Great, effective, clean products and always at a reasonable price."

Jan W.

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Reviews
Supplement Facts

NAD+ vs. NMN vs. NMNH - which one is right for you?

If you're new to NAD+ supplementation, the question isn't whether to support your NAD+ levels - it's where in the pathway to start. Each one enters the salvage pathway at a different point, has a different evidence base, and suits a different type of user. Here's how they compare.

Scroll to compare →

COMPARE NAD+ NMN NMNH
WHAT IT IS in one sentence

The end-stage coenzyme itself — the molecule every cell uses for energy production, DNA repair, and sirtuin activation.

A direct precursor to NAD+ — one enzymatic step away from the active coenzyme.

The reduced (hydrogenated) form of NMN, formulated for greater stability and a longer NAD+-elevation window.
WHERE IT SITS on the salvage pathway

The destination. NAD is what NMN, NMNH, and NR are all converted into inside the cell.

One step upstream of NAD+. Converted via NMNAT enzymes once it reaches the cytoplasm.

Same step as NMN, but enters in a reduced state — research suggests this changes how it's processed and how long it stays elevated.
BIOAVAILABILITY PROFILE what we know

Direct oral NAD is partially broken down in digestion before reaching cells. The mechanism by which oral NAD raises tissue NAD+ is debated in the literature — most likely via downstream salvage intermediates.

Rapidly absorbed orally; short half-life, which is why split-dosing (morning + afternoon) is recommended. A 2026 head-to-head trial in iScience measured a 67% rise in blood NAD+ at a 1,200 mg dose.

Preclinical data suggests NMNH produces higher and longer-lasting NAD+ elevation than standard NMN — though most of this evidence is from animal studies, not yet replicated in published human trials.
CLINICAL EVIDENCE human data summary

Sparse. Most published human research in the NAD space is on the precursors (NR and NMN), not on direct oral NAD as a finished supplement. Mechanism studies dominate the literature.

Multiple human pharmacokinetic trials. Some product-level studies on branded forms (e.g. Uthever). The 2026 iScience crossover is the most recent peer-reviewed comparison.

Mostly preclinical and early-stage. The often-quoted figures comparing NMNH to NMN come from animal studies — promising signal, but not yet validated by published human RCTs.
TYPICAL DAILY DOSE Double Wood serving

500 mg / day  (2 caps × 250 mg)

Taken on an empty stomach, in the morning.

250 mg / day  (2 caps × 125 mg)

Split-dosed: one capsule on waking, one in the afternoon.

250 mg / day  (2 caps)

Taken on an empty stomach.
BEST FOR who picks this

Customers who want to supplement the active coenzyme directly, often as a complement to a precursor protocol. Lowest barrier to entry at $1.33 per serving.

Longevity-focused users following Sinclair-style protocols, or anyone wanting the most-studied direct precursor. Strongest fit for split-dosing routines.

Early-adopters who track longevity research closely and want the newest, most-stable NMN form. A reasonable next step for users not satisfied with standard NMN.
SHOP View NAD+ → View NMN → View NMNH →

Still not sure? A reasonable rule of thumb: If you want the most-discussed direct precursor in longevity protocols, start with NMN. If you want the newest NMN form with promising preclinical data, NMNH is the early-adopter pick.

Pairs well with

Powerful alone, stronger together. NAD+ Supplement delivers targeted support on its own, but combining it with complementary ingredients can help create a more holistic and balanced approach to wellness.

  • Resveratrol Supplement

    Resveratrol offers antioxidant support and is found in grapes and wine, contributing to your wellness journey.

  • TMG Supplement

    Trimethylglycine (TMG) supports your overall well-being, helping to maintain healthy levels in your body. It's a great addition to your daily routine.

Frequently Asked Questions

What is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of the body, involved in cellular energy metabolism and fundamental biological processes.

Is this real NAD+, or a precursor like NR relabeled?

This product provides 500mg of NAD+ itself, verified at 95% purity, as the single active ingredient, not nicotinamide riboside relabeled as NAD+, and not a small amount tucked inside a larger blend.

Why do NAD+ levels matter as we age?

NAD+ is involved in normal cellular energy metabolism. Research reviews have reported that NAD+ metabolism changes with age. This doesn't mean NAD+ supplements treat or prevent age-related disease; it explains why NAD+ has become an area of ongoing research interest.*

What's the difference between NAD+, NMN, NR, and NMNH?

NAD+ is the coenzyme itself. NMN, NR, and NMNH are precursor nutrients the body can use in NAD+ metabolism. This product provides direct NAD+, while NMN, NMNH, and NR Malate are different options for those who prefer precursor-based support. The strongest current human research base exists for the precursors.

How much NAD+ should I take per day?

The recommended daily serving is 2 capsules, providing 500mg of NAD+. Take on an empty stomach, preferably in the morning. Do not exceed the recommended serving unless directed by a healthcare professional.

What are the side effects of NAD+ supplements?

NAD+ supplements are generally well-tolerated, but some individuals may experience mild side effects such as nausea, headaches, fatigue, or digestive discomfort. Consult a healthcare provider if side effects persist or worsen.

Is Double Wood's NAD+ third-party tested, and where can I find the COA?

Every batch tested. Third-party tests by ISO/IEC 17025 accredited labs. COAs published openly. Testing verifies identity, potency, and heavy metals. The Certificate of Analysis is publicly available on this page.

Overall rating: 4.7058825 / 5 from 17 reviews.

AI Generated Review Summary

Summary topics

Review topics: [quality, term, supplement].

Review highlights

Reviews

"Hey friend I have it now. Thank."

— Niecy45 (4/5)

Feeling younger everyday! 🤩

"Great product from an amazing company! Love the clean supplements! Price is a bonus too!"

— Anthony O. (5/5)

Good supplement

"This is a good supplement with a nutritious diet to keep your energy up."

— Robert S. (5/5)

I haven't felt much different.

"It hasn't been a month yet. Hoping it will kick in soon I have read the liquid goes into your system quicker is there any truth to this?"

— Marcia A. (5/5)

Excellent Quality

"Quality product, good packaging, consistent product, long term daily maintenance."

— Aaron K. (5/5)

I rarely see obvious benefits right away. . .

"As a chemist and biologist, I am intrigued by the theoretical benefits of many supplements but typically find that I can see no real changes -- short term or long term. Of course, if longevity is the long-term goal, I suppose we have to wait for the review from the afterlife, but these seem to provide me with more energy to complete more tasks in my hectic 365-day work year."

— Stephen G. (5/5)

"Excellent"

— Mark (5/5)

"Awesome product"

— Ivan (5/5)

"Very good"

— John (5/5)

Doing well

"So far so good. It's only been a week but I've tolerated this week without bad side effects and that's a big deal for me. I've noticed an increase on energy and have not required coffee! That alone in such a short time is wonderful!!"

— Abigail (5/5)

Q&A

Is it ok to break open the capsules and put in water to drink instead of swallowing the capsules?
Yes, it is generally safe to break open NAD+ (nicotinamide adenine dinucleotide) capsules and mix the contents with water. However, mixing the contents with water could result in faster absorption, but it may also lead to degradation as the product is sensitive to light, moisture, and air.
Double Wood NAD+ supplement bottle, 60 capsules, 500mg per serving

NAD+ Supplement

From

$ 39.95

Primary Benefit

Healthy Aging

Other Benefits

Product Form

Capsule
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