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Brain Health Supplements


  • Best Seller

    Magnesium L-Threonate (Magtein) Supplement

    Sleep
    Anxiety & Stress
    Brain Health

    From

    $ 30.95

  • Best Seller

    Lion's Mane Mushroom Supplement

    Brain Health
    Immune Health

    From

    $ 22.95

  • Best Seller

    Astaxanthin Supplement

    Antioxidants
    Brain Health
    Immune Health

    From

    $ 25.95

  • Alpha GPC Supplement

    Brain Health
    Focus & Energy

    From

    $ 19.95

  • CDP Choline Supplement

    Brain Health
    Focus & Energy

    From

    $ 19.95

  • Phosphatidylserine Supplement

    Brain Health
    Anxiety & Stress
    Focus & Energy

    From

    $ 22.95

  • N-Acetyl Cysteine (NAC) Supplement

    Liver Health
    Antioxidants
    Brain Health

    From

    $ 29.95

  • Magnesium Complex Supplement

    Sleep
    Brain Health

    From

    $ 19.95

  • Spermidine Supplement

    Healthy Aging
    Brain Health
    Hair Skin and Nails

    From

    $ 39.95

  • Creatine Powder

    Active Lifestyle & Fitness
    Brain Health

    $ 27.95

  • Pterostilbene Supplement

    Brain Health
    Focus & Energy
    Heart & Vessels

    From

    $ 19.95

  • Turkey Tail Mushroom Supplement

    Immune Health
    Antioxidants
    Gut Health

    From

    $ 19.95

  • PQQ (Pyrroloquinoline quinone) Supplement

    Healthy Aging
    Brain Health
    Heart & Vessels

    From

    $ 19.95

  • Acetyl L-Carnitine (ALCAR) Supplement

    Brain Health
    Active Lifestyle & Fitness
    Focus & Energy

    From

    $ 19.95

  • Methylated Multivitamin

    Healthy Aging
    Brain Health
    Focus & Energy

    From

    $ 29.95

  • Phosphatidylcholine Complex Supplement

    Brain Health
    Focus & Energy

    From

    $ 19.95

  • Uridine Supplement

    Brain Health
    Focus & Energy

    From

    $ 21.95

  • L-Serine Supplement

    Brain Health
    Sleep

    From

    $ 19.95

  • Benfotiamine Supplement

    Heart & Vessels
    Antioxidants
    Brain Health

    From

    $ 19.95

  • Huperzine A Supplement

    Brain Health
    Focus & Energy

    From

    $ 19.95

Overview

Your brain is the most metabolically demanding organ in the body, and it relies on a specific set of nutrients, cofactors, and precursors to maintain memory, learning, and long-term cognitive function. Double Wood's brain health collection features research-backed, single-ingredient supplements chosen for their ability to cross the blood-brain barrier, support neurotransmitter synthesis, or provide direct neuroprotective effects. Because every product contains one active ingredient, you know exactly what you are putting in your body — and exactly what to credit when you feel a difference.

What To Look For

When choosing a brain health supplement, the most important factors are bioavailability (how well the ingredient reaches brain tissue), evidence quality (number of human clinical trials), and dose accuracy. Common goals include memory support, protection against age-related cognitive decline, and enhanced focus. Top ingredients in this category include Magnesium L-Threonate (the only form of magnesium studied to cross the blood-brain barrier at meaningful concentrations), Lion's Mane (linked to nerve growth factor stimulation), Alpha GPC and CDP Choline (acetylcholine precursors), Phosphatidylserine (a phospholipid found in brain cell membranes), and Uridine (an RNA nucleoside involved in synaptic plasticity). Astaxanthin and NAC provide antioxidant support specifically relevant to brain tissue.

Frequently Asked Questions

What is the best supplement for memory and cognitive function?
Magnesium L-Threonate (sold as Magtein) is one of the most studied options for memory support. A 2022 clinical trial found that 2g of Magtein daily improved memory scores in healthy adults over 30 days. Lion's Mane is another well-researched option, studied for its effects on nerve growth factor. Both are available individually so you can assess each one on its own.
What is the difference between Alpha GPC and CDP Choline?
Both are choline sources that support acetylcholine production, but they have different phospholipid profiles. Alpha GPC has a higher choline content by weight and is often preferred for short-term cognitive performance. CDP Choline also provides cytidine, which converts to uridine in the body and supports broader neurological function. Both can be used independently or paired together.
Can I pair brain health supplements together?
Yes. Because Double Wood products are single-ingredient, they are designed with pairing in mind. A common beginner brain health pairing is Magnesium L-Threonate, Alpha GPC, and Lion's Mane. Start each one individually before combining so you can understand how your body responds to each ingredient.
- All Double Wood supplements are single-ingredient, third-party tested for purity and potency, and manufactured in cGMP-certified U.S. facilities. Certificates of Analysis are available for every product.